Coronaviruses
Researchers have reported a rare occurrence of spontaneous tumour shrinkage in colorectal cancer patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). According to their study, three patients experienced tumour shrinkage during their SARS-CoV-2 infection, with two of the patients showing significant reduction in tumour size. The researchers believe
Coronaviruses
Researchers at the University of Lodz, Poland, have been investigating potential treatments for COVID-19. According to a recent study, guggulsterone, a compound found in certain plants, has shown promise as a treatment for the virus. The study, published in the journal Molecules, found that guggulsterone can bind to the ADP
Coronaviruses
Scientists at Emory University School of Medicine have made significant strides in the fight against COVID-19 by developing a hybrid vaccine that protects against both influenza and SARS-CoV-2 viruses. The innovative vaccine design uses influenza virus-like particles to incorporate a protein from SARS-CoV-2, inducing a strong antibody response and providing
Coronaviruses
Scientists and researchers have been using insights from previous outbreaks, such as SARS and MERS, to develop antiviral drugs against COVID-19. A recent study from the Manipal Academy of Higher Education has employed virtual screening and molecular dynamics to identify potential therapeutic compounds for SARS-CoV-2. The research found that natural
Coronaviruses
The U.S. Food and Drug Administration has announced several key updates, including the approval of COMIRNATY (COVID-19 Vaccine, mRNA) for individuals between 12 and 15 years old, as well as the finalization of guidance for animal food facilities to develop a food safety plan. The agency has also authorized
Coronaviruses
Researchers from the University of Business and Technology have explored a within-host model of SARS-CoV-2/malaria coinfection, analyzing the interactions between uninfected and infected red blood cells, free SARS-CoV-2 particles, and antibodies. The study concluded that the shared immune response reduces the concentrations of malaria merozoites and SARS-CoV-2 particles in
Coronaviruses
Research from the Institute of Biological Information Processing in Julich, Germany, has identified the 3C-like protease (3CL[superscript]pro) as a vital component in the life cycle of SARS-CoV-2, making it a promising drug target. The study discovered that a cationic peptide from rattlesnake venom, known as crotamine, can be
Coronaviruses
The French Society of Pharmacology and Therapeutics (SFPT) released guidelines for managing drug-drug interactions with nirmatrelvir in patients treated for COVID-19. The guidelines were developed by a team of 18 clinical pharmacologists who searched the scientific literature to provide recommendations on the use of nirmatrelvir/ritonavir in combination with other
Coronaviruses
Researchers from the University of Maryland have analyzed the humoral immune responses of solid organ transplant recipients to SARS-CoV-2 vaccination, revealing an increased risk of COVID-19-related mortality in these patients. The team found that a third vaccine dose resulted in improved antibody responses against most SARS-CoV-2 variants, except the omicron
Coronaviruses
A new study on the impact of COVID-19 lockdowns on air pollution and greenhouse gas emissions has been published, highlighting significant decreases in these emissions in major polluting countries. The research, funded by the Nippon Foundation and the University of British Columbia, notes that while lockdowns have led to a
Coronaviruses
Researchers at University College Dublin have made a significant breakthrough in COVID-19 research by developing a protocol for recovering high-quality RNA from positive SARS-CoV-2 rapid antigen diagnostic tests (RADTs). This discovery has the potential to extend the diagnostic utility of RADTs, enabling the rapid identification of circulating variants and tracing
Coronaviruses
Scientists at Newsoara Biopharma Co. Ltd. have designed a recombinant expression vector that can produce highly potent neutralizing antibodies against SARS-CoV-2. The virus, responsible for the COVID-19 pandemic, has caused over 2,000,000 deaths worldwide. The recombinant expression vector is designed to deliver and produce neutralizing antibodies that can
