Stem cells
Researchers at the Mayo Clinic have conducted a retrospective analysis of 138 patients with chronic myelomonocytic leukemia (CMML) who underwent allogeneic stem cell transplantation (ASCT). The study found that patients who transitioned to ASCT while in the chronic phase of the disease (Group A) displayed superior post-transplant survival (PTS) compared
Stem cells
The animal health biotechnology company Gallant has bolstered its Board of Directors with the appointment of Misti Ushio, PhD, and Doug Drew, MBA. Ushio, a seasoned biotech executive with over 25 years of experience, brings expertise in translating breakthrough science into commercially successful companies. She is a Managing Partner at
Stem cells
Researchers at the Medical University of Silesia in Poland have conducted a study to evaluate the long-term outcomes of autologous stem cell transplantation (ASCT) in patients with mantle cell lymphoma (MCL). The study, published in the Annals of Hematology, included 119 patients who underwent ASCT between 2007 and 2024 in
Stem cells
Researchers from the National Cancer Institute (NCI) have presented a study on the effectiveness of umbilical cord blood transplantation (UCBT) for patients with chronic granulomatous disease (CGD) who lack suitable HLA-matched donors. The study, published in Transplantation and Cellular Therapy, found that UCBT can provide an effective alternative for these
Stem cells
Researchers from Capital Medical University have conducted a retrospective cohort study to evaluate the prognostic impact of baseline variables on survival after autologous stem cell transplantation in multiple myeloma patients. The study, published in Transplant Immunology, analyzed data from 350 patients who underwent a first autologous hematopoietic stem cell transplantation
Stem cells
A dual-center retrospective study of adolescents and young adults with acute lymphoblastic leukemia (ALL) who underwent allogeneic hematopoietic cell transplantation (HCT) in second remission (CR2) between 2010 and 2022 has been conducted. The study aimed to evaluate the outcomes of HCT in this patient population. The findings suggest that outcomes
Stem cells
Researchers at the University Hospital Tubingen conducted a retrospective analysis on the effectiveness of methotrexate (MTX) versus mycophenolate mofetil (MMF) prophylaxis in allogeneic hematopoietic cell transplantation (allo-HCT) for chronic myeloid malignancies. The study, which analyzed 13,699 patients from 321 centers, found that MTX prophylaxis was associated with reduced overall
Stem cells
Research from the University of Alabama Birmingham has revealed a significant association between clonal hematopoiesis and the risk of venous thromboembolism (VTE) in patients who have undergone autologous peripheral blood stem cell transplantation for lymphoma. According to the study, patients with clonal hematopoiesis were found to have a higher risk
Cancer
Researchers at the National Autonomous University of Mexico (UNAM) have discovered that molecular iodine (I) has differential antiproliferative actions on progenitor and stem populations from chemoresistant cancer cells. The study aimed to compare the effect of I supplementation on progenitor and stem populations with low and high invasiveness in mammary
Cancer
Reece Khan, a 16-year-old boy, was diagnosed with acute lymphoblastic leukemia (ALL) at the age of 11 in March 2020. After three and a half years of treatment, he was told he was cancer-free 18 months ago. However, on his 16th birthday, he received devastating news that his cancer had
Cancer
On World Blood Cancer Day, Rachael Nixon, a 39-year-old nurse diagnosed with myelofibrosis, a type of blood cancer, is appealing to everyone aged 17-55 and in good health to join the stem cell donor register with DKMS. After a long search, two complete strangers in America have been identified as
Cancer
An Australian cancer patient has traveled 10,000 miles to meet his UK stem cell donor, an extraordinary act of kindness that has saved his life. Luke Melling, 31, flew from Melbourne to Grantham in Lincolnshire to meet Alastair Hawken, the 51-year-old who donated his stem cells to help Melling
