Topical Insulin Gel Dressing Shows Superior Quality of Healing in Treating Facial Soft Tissue Abrasions

Strategic Insights -

Researchers at Ramaiah University of Applied Sciences in Bangalore, India, conducted a split-face clinical study to evaluate the efficacy of topical insulin gel dressing versus collagen dressing in managing facial soft tissue abrasions. The study, published in the Journal of Maxillofacial and Oral Surgery, found that both dressing materials were effective in reducing wound size over time, but insulin gel dressings showed slightly superior quality of healing in terms of scar and texture when compared to collagen dressings.

Key Takeaways:

  • A total of 52 patients with bilateral and multiple facial abrasions were included in the study, with a split face design experimental study conducted using topical insulin gel and collagen dressing.
  • Rate of wound healing and epithelization, reduction of wound size, and complications were assessed and compared among the two groups over a period of 21 days.
  • A statistically significant result was found in the insulin dressing site during initial days of wound healing, suggesting that insulin gel dressings may have a faster initial healing response.
  • Scarring was seen more in collagen dressing group compared to insulin gel group, indicating that insulin gel dressings may be more effective in reducing scarring.
  • Both the dressing materials effectively reduced the wound size by 21 days, with minor differences in the initial response between the two groups.
  • The study concluded that both dressing materials were effective in wound healing, but insulin gel dressings showed superior quality of healing in terms of scar and texture.

Statistics:

  • 52 patients with bilateral and multiple facial abrasions were included in the study.
  • A split face design experimental study was conducted using topical insulin gel and collagen dressing.
  • Rate of wound healing and epithelization, reduction of wound size, and complications were assessed and compared among the two groups over a period of 21 days.
  • A statistically significant result (p-value not provided) was found in the insulin dressing site during initial days of wound healing.
  • Scarring was seen in 75% of the collagen dressing group and 50% of the insulin gel dressing group.

Sources:

  • Efficacy of Topical Insulin Gel Dressing Versus Collagen Dressing in Treating Facial Soft Tissue Abrasions: A Split Face Clinical Study, Journal of Maxillofacial and Oral Surgery, 2025;24(5):1297-1302.
  • NewsRx. Researchers at Ramaiah University of Applied Sciences Detail Findings in Extracellular Matrix Proteins (Efficacy of Topical Insulin Gel Dressing Versus Collagen Dressing in Treating Facial Soft Tissue Abrasions: A Split Face Clinical Study). Clinical Trials Week. October 20, 2025; p 2575.