Antiarthritic agents

Development of Hypogammaglobulinemia in Rheumatoid Arthritis Patients on Rituximab Treatment Associated with Better Treatment Response

Research conducted at the Ankara University School of Medicine has investigated the frequency of hypogammaglobulinemia development in rheumatoid arthritis (RA) patients receiving rituximab treatment. The study retrospectively evaluated 165 RA patients who received at least two courses of rituximab with a six-month interval between 2010 and 2021. The results showed

Physical Therapists' Attitudes and Beliefs on Treating Knee Osteoarthritis in Saudi Arabia

Researchers at the Royal Melbourne Institute of Technology - RMIT University have conducted a study on the attitudes and beliefs of physical therapists in Saudi Arabia regarding the treatment of knee osteoarthritis. The study, published in the Journal of Clinical Medicine, aimed to explore the physical therapists' views on

Antiarthritic agents

Altered Knee Biomechanics Linked to Worsened Knee Pain and Cartilage Damage in Osteoarthritis

A new study has identified specific gait biomechanical characteristics associated with pain and cartilage damage in individuals with patellofemoral joint osteoarthritis during a stair descent activity. Researchers at the University of California San Francisco (UCSF) conducted a cross-sectional observational study involving 83 participants, 66 of whom completed all components required

Antiarthritic agents

Aerobic Exercise Found to be Most Beneficial in Managing Knee Osteoarthritis

According to a recent systematic review and network meta-analysis, aerobic exercise has been found to be the most beneficial treatment for managing knee osteoarthritis. The study, conducted by researchers from Zhejiang University School of Medicine, included 217 randomised controlled trials involving 15,684 participants. The results showed that aerobic exercise

Antiarthritic agents

Psoriatic Arthritis Research Reveals Key Mechanisms for Treating Enthesitis

Recent research findings have provided new insights into the mechanisms of psoriatic arthritis, a chronic autoimmune disease characterized by inflammation of the entheses, which are the sites where tendons and ligaments connect to bone. The study, led by Hashem Mohammadian, examined the effects of interleukin-17A (IL-17A) inhibition on enthesitis in

Adults

Knee Extensor Power Declines Rapidly with Aging, Increasing Risk of Knee Pain

A study published in The Journal of Rheumatology found a significant correlation between knee extensor power and knee pain in adults with or at risk for knee osteoarthritis. Researchers from the University of Kansas Medical Center and the University of Iowa evaluated the relationship between knee extensor power and changes

Antiarthritic agents

Association Between Abnormal Glucose Metabolism and Rheumatoid Arthritis Revealed

Investigations into autoimmune diseases have led researchers to uncover a significant association between rheumatoid arthritis (RA) and abnormal glucose metabolism. A recent study published in Experimental and Molecular Pathology found that RA patients with Type 2 Diabetes Mellitus (T2DM) and insulin resistance (IR) have a higher incidence of the disease.

Antiarthritic agents

Psoriatic Arthritis Remains Difficult to Treat: Study

Researchers at Hospital Clinic Barcelona have revealed new insights into the challenges of treating psoriatic arthritis, with nearly one-fourth of patients remaining active despite multiple treatments. The study, published in the journal Diagnostics, found that difficult-to-treat (D2T) psoriatic arthritis is associated with disease duration, comorbidities, activity, HLA-B27, and combined therapies.

Antiarthritic agents

New Study Reveals Potential Treatment for Rheumatoid Arthritis Caused by Smoking

A team of researchers from the Southern Medical University in Guangzhou, Guangdong, China has made a groundbreaking discovery that could lead to the prevention and treatment of rheumatoid arthritis (RA) caused by smoking. According to the study, a compound called 3,3'-diindolylmethane (DIM) has shown promise in alleviating

Antiarthritic agents

Advances in Rheumatoid Arthritis Research: CTLA4 and UCP2 as Potential Therapeutic Targets

Scientists at Sun Yat-Sen University have made significant strides in understanding the mechanisms behind rheumatoid arthritis, a chronic autoimmune disease that causes inflammation and pain in the joints. By investigating the role of regulatory T cells (Tregs) in the disease, researchers have identified two key players: CTLA4 and UCP2. These

Antiarthritic agents

New Research on Knee Osteoarthritis Suggests Promising Diagnostic Tool

Researchers from First People's Hospital in Zhejiang, People's Republic of China, have conducted a study to evaluate the diagnostic value of musculoskeletal ultrasound in patients with knee osteoarthritis (KOA). The study, published in the Journal of Musculoskeletal & Neuronal Interactions, aimed to assess the correlation between

Antiarthritic agents

Herbal Interventions Show Promise in Managing Knee Osteoarthritis

Researchers from Burapha University in Chonburi, Thailand, have conducted a systematic review and network meta-analysis to explore the efficacy and safety of herbal interventions, specifically Curcuma longa (CL) and Boswellia serrata (BS), in managing knee osteoarthritis (KOA). The study, published in Complementary Therapies in Medicine, found that modified formulations of

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