Cancer
Researchers at the University of Miami have published a review article in the journal Nanomedicine, highlighting the potential of magnetoelectric nanoparticles (MENPs) in cancer therapy. According to the study, MENPs, which generate electric fields in response to magnetic fields, can be used to target and destroy cancer cells without causing
Cancer
AstraZeneca, a global biopharmaceutical company, has presented data from four major pivotal trials at the European Society for Medical Oncology (ESMO) Congress 2025, showcasing the potential of its diverse portfolio of 18 approved and potential new medicines in various cancer types. The data presented at the conference highlight the company&
Cancer
Scientists at the University of Minnesota have made a significant discovery in the field of cancer therapy. A new study on the transcription factor BCL11B has revealed its crucial role in enhancing the cytotoxicity and antitumor activity of natural killer (NK) cells. The research, funded by the National Cancer Institute
Cancer
Researchers from the Indiana University School of Medicine have shed new light on the potential of neutralizing antibodies against insulin-like growth factor (IGF) in cancer therapy. The study, published in the Journal of Leukocyte Biology, highlights the significance of targeting IGF-I and IGF-II in overcoming treatment resistance. The findings suggest
Cancer
Ferroptosis is a form of non-apoptotic cell death that is critical for cancer therapy. Current research has shown that cysteine metabolism plays a pivotal role in ferroptosis regulation by modulating antioxidant defense, lipid peroxidation, and iron homeostasis. Cancer cells exploit cysteine availability to evade ferroptotic cell death, contributing to tumor
Cancer
Research from Fudan University in Shanghai, China, has shed new light on the role of collagen in cancer development and growth. The study, published in Cancer Pathogenesis and Therapy, reveals that collagen plays a crucial role in creating a three-dimensional framework that supports tumor growth and development. The researchers also
Cancer
Researchers at the Tianjin Medical University Cancer Institute and Hospital have developed a novel solid phase extraction (SPE) method using hydrophobic polypropylene fabric (PPF) for the accurate quantification of tyrosine kinase inhibitors (TKIs) in plasma. This method enables sensitive determination of eight clinically relevant TKIs in plasma, with high extraction
Cancer
Scientists at Instituto de Salud Carlos III have made a significant breakthrough in cancer gene therapy, successfully targeting Ewing sarcoma cells using GGAA promoters and adenoviral vectors. This innovative approach involves expressing the suicide gene thymidine kinase from herpes simplex virus (HSV-TK) in Ewing sarcoma cells, leading to cell death
Cancer
Researchers from Putian University in China have made a significant breakthrough in cancer treatment by developing a nano-photosensitizer that combines chemotherapy and phototherapy to target and kill cancer cells. The innovative nano-photosensitizer, called BAP, uses a single wavelength laser to initiate both photodynamic therapy (PDT) and photothermal therapy (PTT), while
Cancer
Researchers from Universite Claude Bernard Lyon 1 have made a significant discovery in the field of cancer treatment. According to their study, published in the journal Biochimica et Biophysica Acta, the inhibition of nucleotide excision repair (NER) proteins can increase the efficacy of alkylating agents used to treat various cancers.
Cancer
Researchers from the Department of Ultrasound at The First Affiliated Hospital of Harbin Medical University have made a groundbreaking discovery in cancer treatment. By combining two forms of regulated cell death, apoptosis and ferroptosis, their innovative microneedle patch system has shown significant promise in overcoming chemoresistance and improving breast cancer
Cancer
Researchers from Anhui Medical University have made significant discoveries in the field of immunology and autoimmunity, highlighting the potential of Tyrosine Kinase 2 (TYK2) inhibitors in treating various autoimmune diseases and cancers. The study, published in Bioorganic Chemistry, explored the structure and biological features of TYK2, the JAK/STAT signaling
