Biological products
Lava Therapeutics N.V. has been issued a patent for a novel antibody that targets prostate-specific membrane antigen (PSMA) and can stimulate autologous Vg9Vd2 T cells to kill prostate cancer cells. The patent, titled "Antibodies that bind PSMA and gamma-delta T cell receptors," was filed on May 6,
Biological products
A new study from the Faculty of Pharmaceutical Sciences has uncovered a potential solution to managing Aedes aegypti mosquitoes, which are carriers of infectious diseases that affect millions of people worldwide. The research explored the effectiveness of using Persea americana plant extracts to eradicate the vector, with significant larvicidal effects
Biological products
Researchers at the Massachusetts Institute of Technology have developed a new imaging probe called ChERT, which allows for the detection of cholinesterase (ChE) activity in the brain and peripheral regions using magnetic resonance imaging (MRI). This breakthrough could be crucial for studying the basic biology of cholinergic systems and disorders
Biological products
Researchers at the University of Gdansk have made significant advancements in the field of biomaterials, exploring the potential of organic acid-based deep eutectic solvents (OA-DESs) as effective antimicrobial agents. The study reveals that OA-DESs can eradicate methicillin-resistant (MRSA) bacteria, induce significant morphological changes in biofilms, and inhibit the growth of
Biological products
Research conducted at the Technology Center, China Tobacco Fujian Industrial Co. Ltd., has yielded a significant advancement in tobacco formulation design. By applying a computational framework and convolutional neural network (CNN) to tobacco data, the researchers have successfully achieved regional style classification accuracy of 99.54% and style consistency in
Biological products
Research from the Technical University in Germany has demonstrated the efficient manufacturing of complex biopharmaceuticals using innovative downstream processing strategies, specifically membrane chromatography. This approach enables high-throughput separations at elevated flow rates, offering a promising alternative to resin-based systems. The study focuses on the Natrix CH membrane, a novel mixed-mode
Biological products
Scientists at the National Institute for Materials Science in Japan have made a significant breakthrough in developing hemostatic powders that can effectively prevent bleeding after endoscopic submucosal dissection (ESD) for early-stage gastrointestinal cancers. The research team, led by Shima Ito, has developed decanoyl group-modified Alaska pollock gelatin microparticles (C10-MPs) as
Biological products
A team of researchers at the Massachusetts Institute of Technology has successfully developed a low-cost, open-source bioreactor platform for cultivating Synechocystis sp. PCC 6803, a photosynthetic microbe with high potential for capturing excessive atmospheric carbon while generating valuable bioproducts. The bioreactor platform, which incorporates a photobioreactor, a lysis module, and
Biological products
Researchers at the Massachusetts Institute of Technology have developed a new imaging probe called ChERT, which allows for the detection of cholinesterase (ChE) activity in the brain and peripheral regions using magnetic resonance imaging (MRI). This breakthrough could be crucial for studying the basic biology of cholinergic systems and disorders
Biological products
Researchers from Jagiellonian University have conducted a study on the effects of rapidly decellularized adipose tissue on soft tissue vascularization. According to the study published in BMC Biotechnology, the team demonstrated the advantages of decellularized adipose tissue (adipoECM) over defined collagen-based biomaterials for host tissue integration. The research revealed that
Biological products
The patent titled "Anti-TREM2 Antibodies and Related Methods" has been published online on September 30, 2025. The inventors, Aritra Pal, Leonard G. Presta, Venkataraman Sriram, Michel Streuli, and the assignee Portsmouth Merger Sub II LLC, describe an isolated antibody that binds to human TREM2 and competes with the
Apoptosis
Researchers have made significant progress in understanding the immunogenicity of tislelizumab, a humanized anti-PD-1 antibody, which has been analyzed in a comprehensive study involving 3815 patients. The investigation focused on the incidence of anti-drug antibodies (ADAs) and the feasibility of assessing the suitability of validation cut points (VCPs) using statistical
