New Study Reveals Eco-Friendly Method to Eradicate Aedes aegypti Mosquitoes

A new study from the Faculty of Pharmaceutical Sciences has uncovered a potential solution to managing Aedes aegypti mosquitoes, which are carriers of infectious diseases that affect millions of people worldwide. The research explored the effectiveness of using Persea americana plant extracts to eradicate the vector, with significant larvicidal effects observed in all extracts tested. The study's findings have been published in Scientific Reports, a Nature Portfolio journal.

Key Takeaways:

  • The study demonstrated the effectiveness of Persea americana plant extracts in managing Aedes aegypti mosquitoes, with significant larvicidal effects observed in all extracts tested.
  • The extracts showed synergistic insecticidal activity, with the combined effect of ethanol and methanol extract resulting in an LC50 of 15.181 ppm.
  • Phytochemical screening confirmed the presence of alkaloids, flavonoids, tannins, and saponins in some of the extracts.
  • GC-MS analysis identified the plant's constituents responsible for larvicidal action, including fatty acids, heterocyclic compounds, and esters.
  • The study concludes that Persea americana could be considered an economically and eco-friendly control method for curbing the spread of mosquito-borne diseases.

Statistics:

  • 14.606 ppm: LC50 of the ethanol extract
  • 22.548 ppm: LC50 of the methanol extract
  • 146.157 ppm: LC50 of the hexane extract
  • 15.181 ppm: LC50 of the combined synergistic insecticidal activity of ethanol and methanol extract
  • 22.548 ppm: LC50 of the ethanol and hexane extract
  • 54.606 ppm: LC50 of the ethanol and acetone extract

Sources:

  • Synergistic potency and GC-MS analysis of Persea americana extracts against Aedes aegypti. Scientific Reports, 2025,15(1):1-10.
  • NewsRx. New Findings from Faculty of Pharmaceutical Sciences in the Area of Aedes aegypti Described (Synergistic potency and GC-MS analysis of Persea americana extracts against Aedes aegypti). Life Science Weekly. October 21, 2025; p 2751.