Cancer research
Researchers at Bayer HealthCare Pharmaceuticals Inc. have published a study on the long-term responses of patients with metastatic colorectal cancer (mCRC) treated with regorafenib. The study, published in the journal Cancers, analyzed a database of 2444 patients who initiated regorafenib monotherapy between 2013 and 2023. The research found that patients
Cancer research
A new study on prostate cancer research has outlined the current state of treatments and emerging strategies for metastatic castration-resistant prostate cancer (mCRPC), a lethal stage of disease progression. Despite advancements in therapy, resistance to androgen receptor (AR)-directed treatments remains a significant challenge. The study highlights the importance of
Cancer research
Fujian Cancer Hospital has initiated a clinical trial to investigate the efficacy and safety of Sacituzumab Tirumotecan (SacTMT/SKB264) in combination with Iparomlimab/Tuvonralimab (QL1706) as a second-line or later therapy for patients with recurrent or metastatic cervical cancer. The study, registered with the Chinese Clinical Trial Registry (ChiCTR) under
Cancer
New research has shed light on the relationship between immunohistochemical molecular subtypes and lymph node metastasis in endometrial cancer. A study published in the Journal of Obstetrics and Gynaecology Research, led by Hande Nur Oncu and colleagues from the University for Health Sciences in Ankara, Turkiye, evaluated the association between
Cancer metastasis
Researchers have made new discoveries regarding the involvement of lymph nodes in patients with ovarian and colorectal cancer. A study published in the journal Surgery has found that the inferior deep epigastric lymph node basin may serve as a drainage route for the peritoneum, providing an alternative pathway for systemic
Cancer metastasis
A recent study published in the Southern Medical Journal has shed light on the challenges of diagnosing axillary lymph node (ALN) metastases in patients with invasive lobular carcinoma (ILC). Researchers from the H. Lee Moffitt Cancer Center conducted a retrospective review of patients with pT3 ILC between 2014 and 2023,
Cancer metastasis
The Alliance for Clinical Trials in Oncology has launched the ASPIRE trial, a large-scale, Phase III clinical study investigating the effect of adding chemotherapy to current standard treatments for men with advanced prostate cancer. The trial aims to determine whether combining docetaxel, a well-established chemotherapy drug, with hormone therapy and
Cancer metastasis
Mari Grug, a well-known TV presenter in Wales, has been courageously sharing her journey with breast cancer, specifically with metastatic cancer, which has spread to her lymph nodes and liver, since her diagnosis in 2023. Despite the challenges, Mari has become an inspiration to many, emphasizing that a diagnosis of
Cancer metastasis
A new study on oncology - lung cancer has made significant findings on the treatment of organic psychosis associated with brain metastasis. Researchers from the National Cancer Center Hospital in Tokyo, Japan, have reported a case study of a patient in his 80s who developed severe psychiatric symptoms, including delusions
Cancer
Mari Grug, a presenter from Pembrokeshire, is sharing her personal journey with metastatic breast cancer through a documentary titled "Mari Grug: Un dydd ar y tro". The programme, which will air on S4C on October 26 at 9pm, will also be available on S4C Clic and BBC iPlayer
Cancer research
Investigators at the University of Paris have published new research on the effectiveness of anti-EGFR rechallenge therapy in metastatic colorectal cancer. The study, titled "Circulating Tumor Dna Driving Anti-egfr Rechallenge Therapy In Metastatic Colorectal Cancer: the Rasintro Prospective Multicenter Study," suggests that patients with RAS/BRAF wild-type metastatic
Cancer research
A recent study published in Neuro-Oncology has identified novel genomic associations with brain metastasis and progression in colorectal cancer, offering a potential basis for personalized clinical management. Researchers at Memorial Sloan-Kettering Cancer Center analyzed next-generation sequencing data from patients with colorectal cancer to identify genomic features associated with brain metastasis
