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Cancer metastasis

Organic Psychosis in Lung Cancer Patients Treated with Blonanserin Transdermal Patch: A Case Report

Strategic Insights

— 1 min read

A new study on oncology - lung cancer has made significant findings on the treatment of organic psychosis associated with brain metastasis. Researchers from the National Cancer Center Hospital in Tokyo, Japan, have reported a case study of a patient in his 80s who developed severe psychiatric symptoms, including delusions and violent behavior, after brain metastasis from lung cancer. The patient's symptoms were effectively managed with blonanserin transdermal patch, a new treatment option that may be particularly helpful for oncologists and liaison psychiatrists.

Key Takeaways:

  • A patient in his 80s with brain metastasis from lung cancer developed severe psychiatric symptoms, including delusions and violent behavior.
  • The patient's symptoms were effectively managed with blonanserin transdermal patch (40 mg/day) and later stabilized with blonanserin transdermal patch (80 mg/day) with no side effects.
  • Blonanserin transdermal patch may be a helpful option for treating organic psychosis associated with brain metastasis due to its relatively few side effects and ease of administration.
  • The case report highlights the importance of considering alternative treatment options for patients with severe psychiatric symptoms and treatment-resistant psychosis.
  • The research team, led by Ryoichi Sadahiro, consists of experts from the National Cancer Center Hospital in Tokyo, Japan, including Junji Yamaguchi, Saho Wada, Eri Nishikawa, Tatsuto Terada, Rika Nakahara, and Hiromichi Matsuoka.

Statistics:

  • The patient was hospitalized for 53 days after admission.
  • The patient's symptoms improved significantly after starting blonanserin transdermal patch (40 mg/day) and later stabilized with blonanserin transdermal patch (80 mg/day) with no side effects.

Sources:

  • NewsRx. Researchers from National Cancer Center Hospital Report Findings in Lung Cancer (Organic Psychosis due to Lung Cancer Metastasis Accompanied by Severe Psychiatric Symptoms Treated With Blonanserin Transdermal Patch: A Case Report and Literature ...). Medical Devices & Surgical Technology Week. October 26, 2025; p 1882.
  • Organic Psychosis due to Lung Cancer Metastasis Accompanied by Severe Psychiatric Symptoms Treated With Blonanserin Transdermal Patch: A Case Report and Literature Review. Neuropsychopharmacology Reports, 2025;45(4).

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