Cancer research
A study examining brain metastases among patients with metastatic non-small cell lung cancer (mNSCLC) reveals disparities in diagnosis and treatment patterns, particularly in high poverty areas. Data from the Surveillance, Epidemiology, and End Results (SEER) program linked to Medicare claims were used to examine the prevalence of brain imaging at
Cancer
Researchers at the University of California, Los Angeles (UCLA), have developed a novel immunotherapy approach that uses specially engineered immune cells to attack kidney cancer tumors. The innovative "off-the-shelf" therapy, called AlloCAR70-NKT, has shown promising results in preclinical models, demonstrating a multi-pronged attack against kidney cancer. This approach
Cancer
Patients with advanced cancer undergoing palliative radiotherapy for bone metastases experience significant physical and psychological distress, as well as emotional instability, despite the minimally invasive nature of the treatment. A qualitative study exploring patients' lived experiences revealed that healthcare professionals play a crucial role in integrating person-centred care into
Cancer research
A new research study published in the Lancet Oncology journal has found that the combination of lenvatinib and pembrolizumab may be a potential standard treatment for patients with advanced B3 thymoma and thymic carcinoma. The study, conducted by researchers from Paris-Saclay University, involved 43 patients with relapsed or recurrent histologically
Cancer research
A new report published by researchers at Nagoya City University Graduate School of Medical Sciences highlights the risk of cardiac dysfunction in patients with BRAF-mutated colorectal cancer receiving triple therapy consisting of encorafenib, binimetinib, and cetuximab. The study emphasizes the importance of early recognition and management of this adverse event
Cancer research
Research conducted at Thomas Jefferson University has demonstrated the efficacy of ASP-1929 photoimmunotherapy in combination with pembrolizumab in patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC). The phase Ib/II study evaluated the safety and efficacy of the treatment, which involved administering ASP-1929 photoimmunotherapy in combination
Cancer
Advanced sarcomas, a rare and aggressive type of cancer, have limited treatment options. Researchers from Shandong Cancer Hospital in China investigated the efficacy and safety of combining sintilimab and anlotinib, two immunotherapies, in treating advanced sarcomas. The study involved 42 patients with untreated or chemotherapy-resistant sarcomas. The combination treatment resulted
Cancer
Researchers at Hokkaido University in Sapporo, Japan, have made a crucial discovery regarding the effects of radiation therapy on cancer cell migration. According to their study, published in the International Journal of Molecular Sciences, radiation-induced bystander effects can inadvertently enhance tumor cell motility outside the target volume. This finding has
Cancer research
Researchers at Jiangsu University have explored the effectiveness of combining phototherapy with chemotherapy as a treatment strategy for cancer. According to their study, this approach, known as Phototherapy Integrated Chemotherapy (PIC), has shown promising results in eliminating cancer cells while minimizing toxic side effects. The study, supported by the National
Cancer
A recent study conducted by researchers at the Medical University Innsbruck in Innsbruck, Austria, has revealed an exceptional prognosis in POLE-mutated endometrial cancers, even in the presence of brain metastases. According to the research, patients with POLE-mutated endometrioid ECs and brain metastases have survived substantially longer than the median survival
Cancer
Neuroendocrine tumor patients with bone metastases face significant challenges in managing their symptoms and improving overall survival. A recent study conducted at Uppsala University in Sweden aimed to assess the impact of bone metastases on symptoms and overall survival in patients with well-differentiated small intestinal neuroendocrine tumors (Si-NETs). The researchers
Cancer research
The Metastatic Prostate Cancer pipeline has witnessed considerable growth in recent years, with numerous companies and research institutions working to develop innovative treatments. DelveInsight's report provides comprehensive insights into the Metastatic Prostate Cancer pipeline landscape, covering 80+ companies and 85+ pipeline drugs. Metastatic Prostate Cancer is a life-threatening
