Cancer research
Research published in Haematologica has shed light on the impact of minimal residual disease (MRD) on the outcome of hematopoietic stem cell transplantation (HSCT) for childhood acute lymphoblastic leukemia (ALL). The study, conducted within the international phase-III FORUM trial, found that MRD positivity was associated with worse event-free survival (EFS)
Cancer research
A recent study published in Biochimica Et Biophysica Acta-molecular Cell Research has shed light on the role of prolyl isomerase Pin4 in the development of ERα-positive breast cancers. Researchers at Hiroshima University found that Pin4 regulates ERα transcriptional activity and is essential for the proliferation of ERα-positive breast cancer cells.
Cancer research
Researchers at the University of Illinois Chicago have been awarded a three-year, $1.2 million grant from the U.S. Department of Defense Prostate Cancer Research Program to study the variability in the effects of approved treatments for metastatic prostate cancer. The project will leverage data science methods to analyze
Cancer research
A recent study published in the Annals of the American Thoracic Society has shed light on the complexities of non-small cell lung cancer (NSCLC) detection and treatment. The research, conducted at the Icahn School of Medicine at Mount Sinai, aimed to assess outcomes in patients with post-surgical diagnosis of pathologic
Cancer research
A study published in the American Journal of Clinical Nutrition has shed light on the potential health benefits of consuming dietary fiber and omega-3 fatty acids together. The research, conducted by a team of scientists at Fred Hutchinson Cancer Research Center, aimed to investigate the synergistic effects of fish oil
Cancer research
Research from Centre Leon Berard and published in Dermatology Practical & Conceptual suggests that empowerment of primary care medicine through dermoscopy learning is a promising way to overcome the shortage of diagnostic offer for skin cancer screening. In France, a shortage of dermatologists has led to primary care being an
Cancer research
Researchers from the Department of Infectious Diseases have shed new light on the expression heterogeneity of ferroptosis-related genes in hepatocellular carcinoma (HCC). This study, published in the journal Discover Oncology, utilized bioinformatics analysis, weighted gene co-expression network analysis (WGCNA), and single-cell RNA sequencing data to identify key ferroptosis-related gene modules
Cancer research
A team of researchers from Ishikawa Prefectural Central Hospital in Japan has conducted a retrospective analysis of 1,001 patients who underwent gastrectomy for gastric cancer to investigate the relationship between asthma and postoperative complications. The study found that asthma was a significant risk factor for postoperative pulmonary complications and
Cancer research
Researchers at Huazhong University of Science and Technology have made significant discoveries about the role of circular RNAs (circRNAs) in gastric cancer. The study found that hsa_circ_0013729, a specific circRNA, is significantly upregulated in gastric cancer tissues and plays a crucial role in promoting cancer progression. The researchers
Cancer research
A new study from West Kazakhstan Marat Ospanov Medical University aims to quantify the accumulated knowledge about the prognostic value of stomach cancer biomarkers in the context of the morphological Lauren's classification. The analysis of 162 publications from 1995 to 2024 revealed significant growth in research on gastric
Cancer research
A new study published in the Journal of the American Medical Association Network Open highlights the significance of patient navigation in promoting lung cancer screening (LCS) in homeless populations. Researchers from Massachusetts General Hospital conducted a subgroup analysis of the Investigating Navigation to Help Advance Lung Equity (INHALE) pragmatic randomized
Cancer research
A recent study published in Frontiers in Pharmacology has shed new light on the molecular pathogenesis of lung adenocarcinoma (LUAD), a type of non-small cell lung cancer. The research, conducted by a team of scientists from Zhejiang University School of Medicine, has identified two epigenetic-autophagy genes, KDM6B and KANSL1, as
