Cancer research
Intermittent fasting has been found to increase the effectiveness of anti-androgen therapy in treating prostate cancer, marking a significant breakthrough in cancer research. According to a study published in the journal Cancer Research, this alternative dietary approach can reduce the growth of cancer cells and make tumors more sensitive to
Cancer research
A clinical trial, NACRE-2, has been launched by UNICANCER to evaluate the effectiveness of two treatment strategies for elderly patients with locally advanced rectal cancer. The trial aims to assess whether the addition of chemotherapy after short-course radiotherapy is more effective than short-course radiotherapy alone in this patient population. The
Cancer research
Scientists have made breakthroughs in using cutting-edge genetic technology to "personalize" cancer treatments. However, Health and Human Services Secretary Robert F. Kennedy, Jr.'s recent funding cuts for mRNA vaccines have sparked alarm among experts, who fear the decision will have a "profound chilling effect"
Cancer research
Researchers from the First Hospital of China Medical University in Shenyang, People's Republic of China, have made significant progress in understanding and addressing the challenge of cisplatin resistance in laryngeal cancer treatment. By identifying the role of tumor necrosis factor-alpha-induced protein 2 (TNFAIP2) in chemoresistance, the team developed
Cancer research
Researchers at the University of Kentucky have made new discoveries in cancer gene therapy, specifically focusing on the role of OCT4 in mediating lineage plasticity in prostate cancer. The study, published in the journal Biomedicines, highlights the importance of understanding the molecular mechanisms underlying OCT4-driven plasticity to develop novel therapeutic
Cancer research
Pancreatic cancer, one of the most formidable malignancies, has seen minimal improvement in survival rates despite advances in chemotherapy, targeted treatments, and radiation therapy. However, the rapid discovery of the genetic and molecular functions underlying pancreatic cancer has led to new opportunities for targeted therapies, including oncolytic viral therapy. This
Cancer research
Research conducted at Michigan State University has unveiled a revolutionary non-invasive imaging technique called Magnetic Particle Imaging (MPI), which utilizes superparamagnetic iron oxide nanoparticles to track the distribution, survival, and integration of transplanted cells in the lungs of immunocompromised mice. This groundbreaking method offers a potential solution for monitoring cell
Cancer research
Researchers at Yale University have made significant progress in the development of a novel cancer gene therapy. According to a recent study published in Science Translational Medicine, a tumor-targeting, cell-penetrating monoclonal antibody, TMAB3, has been found to form stable, noncovalent antibody/RNA complexes that mediate highly specific and functional delivery
Cancer research
A recent study has shed light on the efficacy of various treatments for patients with prostate cancer who have invaded the seminal vesicles without metastasis. Researchers at the Erasmus University Medical Center Cancer Institute conducted a systematic review and meta-analysis to investigate the effectiveness of treatments such as radical prostatectomy,
Cancer research
Researchers at New York University College of Dentistry have published a new study examining the current applications and future prospects of gene therapy in dentistry. The research highlights the potential of gene therapy in treating various oral diseases, including cancer, cancer-related pain, xerostomia (dry mouth), dental caries, and periodontal disease.
Cancer research
A phase 1 study published in Nature Medicine has shown encouraging results for a vaccine designed to treat patients with pancreatic and colorectal cancer. The vaccine, ELI-002 2P, has been found to generate strong T cell responses in 68% of patients, which correlated with longer recurrence-free and overall survival. However,
Cancer research
A recent study published in Materials Today Bio has shed light on the critical pathophysiological mechanism driving metastatic progression in colorectal cancer. Researchers from Xi'an Jiaotong-Liverpool University have developed a biomimetic composite hydrogel (GHP4a) that mimics the tumor microenvironment (TME) complexity, promoting cell proliferation and differentiation while enhancing
