Cancer research
Researchers at Jiangsu University in Jiangsu, People's Republic of China, have made a significant discovery in the field of oncology, developing a nanoparticle therapy that enhances the therapeutic potential of curcumin for lung cancer treatment. The study, which received financial support from the Medical Education Collaborative Innovation Fund
Cancer research
Researchers from Chettinad Hospital and Research Institute in Tamil Nadu, India, have investigated the potential of a novel nanoparticle-based cancer treatment in a recent study. The treatment, which combines cerium oxide nanoparticles with the anticancer drug doxorubicin, has shown promising results in preclinical studies, inhibiting the growth of cancer cells
Cancer research
Fujian Cancer Hospital has initiated a Phase 2 clinical trial to assess the efficacy and safety of two combination chemotherapy regimens for treating metastatic colorectal cancer. The trial, launched on July 17, will randomize 44 patients with primary left-sided, RAS and BRAF wild-type metastatic colorectal cancer to receive either FOLFOXIRI
Cancer
Researchers from Beijing Normal University have made a significant advancement in cancer gene therapy with the design of a versatile block polyester vector, BFN2. This innovative nanoplatform combines the benefits of photodynamic therapy and targeted gene silencing, effectively overcoming the limitations of each individual approach. According to the study, the
Cancer research
Cancer patients undergoing contemporary systemic anticancer therapies are at high risk of developing venous thromboembolism (VTE), a potentially life-threatening condition. To identify patients with high VTE risk who may benefit from primary thromboprophylaxis, several risk assessment models (RAMs) have been developed. However, the performance of these RAMs has not been
Cancer
Researchers at the University of Texas MD Anderson Cancer Center have made a groundbreaking discovery in understanding how genetic disorders, such as sickle cell disease (SCD), affect cancer immunotherapy. According to a new report published in the journal Immunity, SCD alters the 3D genome architecture of CD8+ T cells, leading
Cancer
Researchers have made a significant breakthrough in the treatment of severe hemophilia B, a rare bleeding disorder, using adeno-associated virus (AAV)-mediated gene therapy. The study, conducted at the Royal Free Hospital in London, involved 10 men with severe hemophilia B who received a single intravenous infusion of the scAAV2/
Cancer treatment
mRNA cancer vaccines, leveraging technology from the COVID-19 pandemic, are rapidly evolving and have the potential to redefine oncology standards of care with targeted immunotherapy. Over 60 mRNA cancer vaccine candidates are currently under development, with a few already in mid- and late-stage clinical trials. These vaccines function by teaching
Cancer research
Traumatic brain injury and hypoxic-ischemic encephalopathy are major causes of long-term neurological disability in children, with limited options for effective neuronal recovery. Recent research has highlighted the therapeutic potential of nerve growth factor (NGF) in promoting neural repair through mechanisms such as neuroprotection, neurogenesis, and the modulation of neuroinflammation. A
Cancer
Scientists at Shanghai Jiao Tong University have made a groundbreaking discovery in the field of cancer gene therapy, developing an in situ injectable, sustained-release hydrogel drug delivery system that has shown remarkable promise in preventing postoperative tumor recurrence. According to the research, the system, known as TL-Lip-CD80Fc@Gel, combines immunotherapy
Cancer research
Researchers from Sichuan University have published a new report on the potential of bacterial outer membrane vesicles (OMVs) in cancer gene therapy. The study, published in MedComm - Biomaterials and Applications, demonstrates the unique properties of OMVs that make them promising avenues for clinical translation, including their use as vaccines,
Cancer research
Researchers from Davangere University in Karnataka, India, have made a significant discovery in the fight against lung cancer. According to a new study published in the journal Next Nanotechnology, they have successfully biosynthesized silver nanoparticles using the ethyl acetate extract of Aristolochia bracteolata Lam. The study reveals that these nanoparticles
