Cancer research
Researchers at Norfolk State University have made a significant discovery in the fight against lung cancer. Using cerium oxide nanoparticles, synthesized from turmeric rhizomes, they have demonstrated enhanced potential as drug carriers, exhibiting anti-inflammatory, anticancer, antimicrobial, and anti-oxidant therapies. The study aimed to investigate the anticancer effects of these nanoparticles
Cancer research
Researchers from Davangere University in Karnataka, India, have made a significant discovery in the fight against lung cancer. According to a new study published in the journal Next Nanotechnology, they have successfully biosynthesized silver nanoparticles using the ethyl acetate extract of Aristolochia bracteolata Lam. The study reveals that these nanoparticles
Cancer
Researchers at McGill University have made a groundbreaking discovery in the field of cancer immunotherapy, developing a dual knockout approach that targets two key immune checkpoints, PD-L1 and Galectin-9 (Gal-9), to improve anti-tumor immunity. According to a recent study published in the journal Biomaterials, the researchers used a nanoparticle-assisted CRISPR-Cas9
Cancer
Researchers at Ezhou Central Hospital have made significant progress in cancer gene therapy, developing a novel DNA delivery carrier that combines photothermal therapy with gene therapy to target cancer cells. This innovative approach has shown promise in treating cancer and has been peer-reviewed in the journal Bioorganic Chemistry. The researchers
Cancer
Researchers at Pondicherry University in India have made a significant breakthrough in cancer gene therapy using multifunctional liposomes that can diagnose and treat cancer simultaneously. The study, published in ACS Applied Bio Materials, utilizes quercetin-encapsulated Dy-doped magneto-liposomes that exhibit improved efficacy and better radical oxygen scavenging ability. These liposomes have
Cancer research
Researchers at the Institute for Cancer Research and Treatment (IRCCS) Neuromedicine have published a comprehensive review of the advancements in hemostasis genetics over the past five decades. The study highlights the transition from understanding rare Mendelian disorders to exploring complex traits influencing cardiovascular disease risk. By analyzing the historical development
Cancer
Adoptive gamma delta T cell therapy has emerged as a novel and promising approach in cancer treatment, leveraging the unique ability of gamma delta T cells to recognize and destroy cancer cells without the requirement of tumor-specific antigens or genetic modifications. This immunotherapy modality possesses characteristics of both innate and
Cancer research
Research from Wuhan University of Science and Technology in Xiangyang, People's Republic of China, has shed light on the challenges and opportunities in treating non-small cell lung cancer (NSCLC) that has a Kirsten rat sarcoma viral oncogene homolog (KRAS) mutation. The study highlights the potential of immunomodulatory therapy
Cancer research
Research conducted by the H. Lee Moffitt Cancer Center and Research Institute has revealed the mechanisms underlying the immunosuppressive ability of neutrophils in brain tumors. The study found that hypoxia drives histone lactylation, which regulates arginase-1 expression, required for T-cell suppression. This study identifies histone lactylation as a potential therapeutic
Cancer
Researchers at the Birla Institute of Technology and Science have made significant progress in understanding the mechanisms of cancer progression and the potential of cancer immunotherapy. The study, published in Frontiers in Pharmacology, highlights the role of regulatory T cells (Tregs) in supporting cancer progression and the importance of targeting
Cancer research
A large population-based cohort study using data from the US National Cancer Database (NCDB) has found that immunotherapy use increased significantly for metastatic head and neck squamous cell carcinoma (mHNSCC) treatment from 2013 to 2020. The study, led by researchers from the University of Pennsylvania, analyzed data from over 5,
Cancer
Researchers from the Materials Department have detailed new data in cancer gene therapy, showcasing the potential of surface-modified carbon dots (CDs) in targeted cancer therapies. According to the study, modified CDs have demonstrated remarkable potential in targeted drug delivery systems, enhancing solubility and specificity in tumor sites while minimizing systemic
