Cancer
Samuel Priestly, a 14-year-old soccer enthusiast, asked his mother, Sharon, if he had a brain tumor due to recurring headaches. The diagnosis of pilocytic astrocytoma, a low-grade childhood brain tumor, was confirmed in July 2018. Samuel underwent multiple surgeries, chemotherapy, and proton beam therapy, but unfortunately, passed away at 18
Cancer
Researchers at the University of California, Los Angeles (UCLA), have developed a novel immunotherapy approach that uses specially engineered immune cells to attack kidney cancer tumors. The innovative "off-the-shelf" therapy, called AlloCAR70-NKT, has shown promising results in preclinical models, demonstrating a multi-pronged attack against kidney cancer. This approach
Cancer
Patients with advanced cancer undergoing palliative radiotherapy for bone metastases experience significant physical and psychological distress, as well as emotional instability, despite the minimally invasive nature of the treatment. A qualitative study exploring patients' lived experiences revealed that healthcare professionals play a crucial role in integrating person-centred care into
Cancer
A recent study published in the American Journal of Gastroenterology has shed light on the effectiveness of low-literacy instructions in enhancing colorectal cancer screening adherence. The study, conducted by researchers at the Hutchinson Institute for Cancer Outcomes Research, involved 13,971 English-speaking patients and 508 Spanish-speaking patients who were eligible
Cancer
UCLA researchers, led by Dr. Amar Kishan, professor and executive vice chair of radiation oncology at the David Geffen School of Medicine at UCLA, have been awarded a $2 million grant from ViewRay Systems, Inc. to support groundbreaking clinical trials in MRI-guided radiotherapy. This innovative technique combines real-time imaging with
Cancer
Recent research from Kwara State University has shed light on the challenges and opportunities in cancer immunotherapy, particularly with the use of interleukin-12 (IL-12) based strategies. The study aims to address the translational challenges and clinical implications of IL-12 therapy, which has shown promising therapeutic potential in treating various cancer
Cancer
Researchers from the Mayo Clinic have made a groundbreaking discovery in the field of cancer gene therapy. By leveraging preexisting anti-viral memory responses, they have found a way to focus high-affinity T cell responses into tumors, leading to cancer cures. This innovative approach utilizes oncolytic viruses or chimeric antigen receptors
Cancer
Research conducted at the Iran University of Science and Technology has led to significant advancements in cancer gene therapy, utilizing the body's immune system to target and eliminate malignancies. The study highlights the potential of chitosan, a naturally derived polysaccharide, in enhancing therapeutic efficacy, safety profiles, and precise
Cancer
Research from Seoul, South Korea has shed new light on the potential of DNA damage response (DDR) inhibitors as a targeted cancer therapy. Current study results have found that impaired genomic stability is a hallmark of many cancers, and that DNA repair mechanisms serve as critical safeguards for maintaining genomic
Cancer
A team of researchers at the Universita degli Studi di Padova has made significant strides in cancer gene therapy, discovering that connexin hemichannel blockade can disrupt glioblastoma progression, suppress invasiveness, and reduce hyperexcitability in preclinical models. The study, published in Cell Communication and Signaling, found that the monoclonal antibody abEC1.
Cancer
Recent research has shed light on the efficacy and safety of a new treatment regimen for advanced endometrial cancer (aEC). The study, conducted by researchers at Texas Tech University Health Sciences Center, compared the use of lenvatinib combined with pembrolizumab (LVB + PMB) to chemotherapy in patients with aEC. The findings
Cancer
Researchers from Jamia Hamdard University have discovered that CD4 T-cells play a crucial role in cancer immunology, and novel drug delivery systems, particularly nanoparticle-based formulations, can enhance antitumor immune responses while minimizing systemic toxicity. The study aimed to explore the immunological significance of CD4 T-cells in cancer and their modulation
