Cancer
Researchers at the Center for Biotechnology Sfax in Tunisia have successfully synthesized silver nanoparticles (AgNPs) using plant extracts and demonstrated their potent antimicrobial, anti-biofilm, and anticancer properties. The study explored the potential of AgNPs derived from Teucrium polium (Tp), Teucrium marum (Tm), and Punica granatum (Pg) for biomedical applications, revealing
Cancer
A new research study has been published in Molecular Imaging and Biology, outlining the steps for radiolabeling the antibody trastuzumab with zirconium-89 (89Zr) and copper-64 (64Cu) for positron emission tomography (PET) imaging. The study, conducted by researchers at Washington University, aims to provide a guide for conjugating trastuzumab with chelators
Cancer
Cancer researchers at China Medical University have made a significant breakthrough in the development of antibodies to target cancer cells expressing the CXC chemokine receptor 4 (CXCR4), a key player in various types of cancer. By employing the AlphaFold3 algorithm to predict interaction sites between ligands and GPCRs, the team
Cancer
Dawn Clegg, a 51-year-old receptionist, has been diagnosed with sarcoma, the UK's rarest and incurable cancer, after experiencing chest pain initially thought to be a side effect of Mounjaro weight loss medication. Despite undergoing chemotherapy, her prognosis is terminal, with doctors unable to pinpoint the exact type of
Cancer
According to a recent study published in JAMA Oncology, investigators conducted a systematic review and individual participant data meta-analysis to examine cancer-specific and patient survival among solid organ transplant recipients (SOTRs) with advanced-stage cancer receiving immune checkpoint inhibitors (ICIs). The study found that cancer outcomes in SOTRs varied by cancer
Cancer
Pediatric alopecia caused by cancer treatment is a significant concern, affecting the mental health and quality of life of children. Research has shown that chemotherapy-induced alopecia and radiation-induced alopecia have varying degrees of severity, depending on the treatment type, mechanism of action, and damage-response pathway involved. Currently, there are no
Cancer
Research has demonstrated that allele-specific DNA methylation (ASM) is critical in understanding the complex genetic and epigenetic mechanisms that regulate gene transcription. Recent studies have shown that ASM is enriched in gene enhancer regions and is increased in cancer tissues compared to normal tissues. A new study has developed CanASM,
Cancer
Researchers at Keele University have embarked on a groundbreaking study to explore the chemical makeup of calcifications caused by prostate cancer. The investigation, supported by Cancer Research UK, aims to identify new markers for early diagnosis by analyzing the elements present in these calcifications. By examining calcified prostate tissue in
Cancer
Researchers at Ajou University in South Korea have developed a novel, compact hyperspectral imaging system with artificial intelligence (AI) that can diagnose gastric cancer accurately based on intrinsic tissue optical properties. The system, which utilizes structured illumination and hyperspectral imaging, was found to be effective in identifying cancer tissue among
Cancer
A groundbreaking new study published in the journal Nature Cancer reveals that radiation therapy can overcome immunotherapy resistance in certain cancers, offering new hope for patients whose tumors have become resistant to treatment. Researchers from the Johns Hopkins Kimmel Cancer Center and the Netherlands Cancer Institute found that combining radiation
Cancer
Pittsburgh, Pennsylvania, a team of researchers from the University of Pittsburgh Medical Center has made a groundbreaking discovery in the field of cancer gene therapy. According to the study, immuno-oncology has evolved significantly over the past century, with the introduction of immune checkpoint blockade (ICB) in the last 15 years
Cancer
Research conducted at Sichuan Integrative Medicine Hospital in Chengdu, People's Republic of China, has explored the predictive value of certain detection indexes and pathological serum levels in patients with early gastric cancer who underwent radical surgery. The study retrospectively analyzed clinical data of 297 EGC patients admitted to
