Cancer
A new study has made a significant advancement in immunotherapy for patients with ALK/EGFR wt resectable non-small cell lung cancer (NSCLC). Researchers from the IRCCS Regina Elena National Cancer Institute used a combination of deep molecular profiling, spatial transcriptomics, and serum proteomic profiling to achieve a complete pathologic response
Cancer
Kara Tointon, a well-known actress from the soap opera EastEnders, has spoken publicly about her decision to undergo a double mastectomy after discovering she carried the BRCA1 gene, which puts her at a high risk of developing cancer. Working with the gynaecological cancer charity the Eve Appeal, Tointon shared her
Cancer
Researchers from Jinan University have discovered that the RNA methyltransferase METTL1 is highly expressed in various types of tumors and is associated with poor prognosis and immune infiltration. The study published in the Guangxi Yike Daxue xuebao journal found that METTL1 expression was significantly higher in cancer tissues compared to
Cancer
Researchers have developed a droplet-based microfluidic platform to track and analyze the behavior of natural killer (NK) cells, a crucial component of the immune system. This innovative platform monitors NK cell-mediated cytotoxicity against K562 cancer cells in real-time, providing valuable insights into the mechanisms of NK cell function. The study
Cancer
A comprehensive review on cancer immunotherapy has been published, providing insights into the historical evolution, underlying mechanisms, and diverse strategies of cancer treatment. The review examines the clinical applications and ongoing preclinical advancements of immune checkpoint inhibitors, cancer vaccines, and adoptive cell transfer, highlighting the challenges posed by immune evasion
Cancer
Former EastEnders actress Kara Tointon has revealed she underwent a double mastectomy following a gene test that revealed she carried the BRCA gene, which puts her at a high risk of breast and ovarian cancer. The 41-year-old actress, who also appeared in dramas such as The Teacher and Mr Selfridge,
Cancer
Despite being diagnosed with stage three bowel cancer last year, Andy Spary, 39, is focusing on the positive and has already started training to run the 2026 London Marathon. The carpenter from Tunbridge Wells, Kent, was diagnosed after experiencing extreme pain in his left buttock, which was initially thought to
Cancer
On World Blood Cancer Day, Rachael Nixon, a 39-year-old nurse diagnosed with myelofibrosis, a type of blood cancer, is appealing to everyone aged 17-55 and in good health to join the stem cell donor register with DKMS. After a long search, two complete strangers in America have been identified as
Cancer
Scientists at Sichuan University, in collaboration with National Natural Science Foundation of China (NSFC) and Science & Technology Department of Sichuan Province, have made a significant discovery in cancer gene therapy. Researchers have designed a reactive oxygen species (ROS)-responsive cationic polymer, PFCA, which can deliver the p53 gene to
Cancer
Researchers from the National Cancer Institute (NCI) have highlighted the critical role of biobanks in genetic research, particularly in genome-wide association studies (GWAS) and the integration of multi-omics data. According to a recent study published in Human Molecular Genetics, biobanks have driven transformative insights into the genetic basis of complex
Cancer
Researchers have discovered a small but significant increase in cancer mortality among women in 17 Middle Eastern and North African countries over the last two decades, with breast, ovarian, uterine, and cervical cancer cases and deaths rising with rising temperatures. The study, published in Frontiers in Public Health, found that
Cancer
Researchers from Guangxi, People's Republic of China, have made a significant discovery in the field of personalized medicine. By integrating radiomic features with clinical biomarkers through machine learning approaches, they were able to develop a hybrid model that predicts neoadjuvant chemotherapy response in patients with locally advanced gastric
