Genes
Researchers from Hangzhou Women's Hospital, Hangzhou, People's Republic of China, have identified key genes associated with the pathogenesis of recurrent pelvic organ prolapse (POP). According to a recently published study, the investigation employed DNA microarray analysis of the human genome, which revealed 116 genes associated with
Genes
Researchers at the People's Hospital of Xinjiang Uygur Autonomous Region have made a significant breakthrough in identifying biomarkers for major depressive disorder (MDD) using bioinformatics analysis. The study, which was financially supported by the Science and Technology Department of Xinjiang Uygur Autonomous Region, aimed to identify biomarkers related
Genes
Scientists at Washington University have developed a novel method to modulate protein translation efficiency, a key challenge in various fields of science and industry. The method involves modifying the nucleic acid sequence encoding a protein of interest to produce a modified nucleic acid sequence encoding a second protein. By making
Genes
Investigators at Boston Medical Center have identified gene expression changes related to mucus pathology in chronic obstructive pulmonary disease (COPD). According to a study published in the American Journal of Respiratory and Critical Care Medicine, researchers investigated the link between mucus plug formation and chronic bronchitis in 290 participants from
Diseases
A research team at Penn State has successfully developed disease-resistant cacao plants using gene-editing technology, potentially resolving a significant problem for the global chocolate industry. The innovation, which has been posted online in the Plant Biotechnology Journal, involves editing the gene TcNPR3 in cacao plants, resulting in plants that have
Diseases
Pakistani and Chinese researchers have conducted a groundbreaking study, mapping 47 important genes in wheat that could help develop new varieties resistant to powdery mildew and better equipped to cope with climate challenges. Led by Babar Hussain of the University of Central Punjab and Qasim Raza of the University of
Genetic research
Research published in the journal Microbiology Spectrum revealed significant genetic diversity and antimicrobial resistance among Klebsiella pneumoniae strains isolated from bovine mastitis milk in South Korea. The study found 29 strains, with 23 sequence types, including four novel ones, indicating substantial genetic heterogeneity. The strains showed high resistance rates to
Genetic research
Researchers from Saint-Petersburg State University have made a significant discovery in the field of cancer gene therapy, developing novel biodegradable polymers that can serve as non-viral vectors for gene delivery. In a study published in the journal Polysaccharides, the team led by Viktor Korzhikov-Vlakh demonstrated the synthesis and evaluation of
Genetic research
Researchers from the Air Force Medical University have developed a novel system for precise, ultrasound-driven regulation of gene expression in engineered bacteria, enabling targeted tumor therapy. The study, published in Theranostics, demonstrates the effectiveness of this approach in enhancing anti-tumor immunity while minimizing adverse effects. By using a modular system
Diseases
Scientists at Viralgen, a subsidiary of AskBio acquired by Bayer in 2020, are dedicated to finding cures for diseases affecting a large number of people through cell and gene therapies (CGT). While Parkinson's disease is the most advanced program in Bayer's CGT pipeline, other priority diseases
Genetic research
India's biomanufacturing sector stands at rank 3 in the Asia-Pacific region and rank 12 globally, with pharma exports expected to cross $30 billion this year. The country's bioeconomy has grown significantly, from $10 billion in 2014 to nearly $170 billion today, and is projected to reach
Genetic research
Research conducted by the Indian Council of Agricultural Research (ICAR) Central Institute of Freshwater Aquaculture has shed light on the nutrient utilization capacity of striped murrel during larval development. The study investigated the expression patterns and activity levels of pancreatic a-amylase in striped murrel larvae, revealing significant increases in a-amylase
