Genomes

Genetic research

Whole-Genome Sequencing and Machine Learning Reveal Key Drivers of Delayed Sputum Conversion in Rifampicin-Resistant Tuberculosis

Researchers at First Affiliated Hospital in Zhejiang, People's Republic of China, have published a new study on rifampicin-resistant tuberculosis (RR-TB). The study integrated whole-genome sequencing and machine learning to identify clinical and genomic determinants of sputum culture conversion (SCC) failure in 150 RR-TB patients between 2019 and 2023.

Genetic research

Pediococcus Acidilactici Strain P10: A Promising Probiotic for Animal Health

Research conducted at the National Institute of Genetic Engineering and Biotechnology in Tehran, Iran, has identified a novel probiotic strain, Pediococcus acidilactici P10, isolated from native broiler chickens. This strain demonstrates promising probiotic attributes, including non-hemolytic properties, high survival rates in simulated gastrointestinal conditions, and potent antimicrobial activity against key

Genetic research

Stabilizing Noncanonical DNA Structures with Chemical Cross-links: Breakthrough in Genomics Research

Researchers from Massey University have made a groundbreaking discovery in the field of genomics, finding a way to stabilize noncanonical DNA structures using chemical cross-links. This breakthrough has significant implications for the study of DNA replication, gene expression, and genome maintenance. According to the research, DNA G-quadruplexes (G4s) are noncanonical