Uncontrolled Seizures in Epilepsy Exacerbate Adverse Health and Social Outcomes

Researchers have underscored the critical issue of uncontrolled seizures among individuals with epilepsy, highlighting the increased risk of adverse health and social outcomes, including a higher risk of death. According to a recently published study, approximately 36.2% of US adults with active epilepsy reported experiencing uncontrolled seizures in the past 12 months, while 14.7% were not taking antiseizure medication and had uncontrolled seizures. The prevalence of seizure control among those with active epilepsy varied significantly by annual family income, with individuals from lower-income households experiencing reduced seizure control.

Key Takeaways:

  • Approximately 1.1% of US adults, or 2.9 million individuals, have active epilepsy, with 49.2% experiencing seizure control and 36.2% experiencing uncontrolled seizures while taking antiseizure medication.
  • Individuals with uncontrolled seizures are at a higher risk of adverse health and social outcomes, including increased risk of death.
  • Seizure control varies significantly by annual family income, with individuals from lower-income households experiencing reduced seizure control.
  • Nearly 400,000 adults with active epilepsy reported having uncontrolled seizures without taking antiseizure medication.
  • Improving provider awareness of epilepsy treatment guidelines, enhancing access to specialty care, providing epilepsy self-management supports, and addressing unmet social needs of individuals with epilepsy with uncontrolled seizures are essential opportunities for intervention.
  • Researchers highlight the need to address disparities in seizure control among individuals with active epilepsy, particularly those at lower family income levels.

Statistics:

  • Approximately 1.1% of US adults have active epilepsy (estimated population: 2.9 million).
  • 49.2% of individuals with active epilepsy reported experiencing seizure control.
  • 36.2% of individuals with active epilepsy reported experiencing uncontrolled seizures while taking antiseizure medication.
  • 14.7% of individuals with active epilepsy reported having uncontrolled seizures without taking antiseizure medication.
  • Seizure control among individuals with active epilepsy varies significantly by annual family income, with individuals from lower-income households experiencing reduced seizure control.
  • The prevalence of seizure control among individuals with active epilepsy is as follows:

+ PIR ≤ 1.0: 16.4%

+ PIR 1.0 - 2.0: 28.7%

+ PIR > 2.0: 55.0%

Sources:

  • Epilepsy & Behavior (2024;157)
  • National Health Interview Survey (NHIS) (2021 and 2022)
  • National Center for Chronic Diseases Prevention and Health Promotion (2024)
  • NewsRx LLC (2024)