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Asthma

Biologics Improve Quality of Life in Severe Asthma Patients

Strategic Insights

— 1 min read

Research conducted at Inje University College of Medicine in Busan, South Korea, has found that biologics significantly improve quality of life in patients with severe asthma. The study, published in the World Allergy Organization Journal, evaluated the effectiveness of different biologics in treating severe asthma and found that they equally improved quality of life in patients.

Key Takeaways:

  • The study evaluated the quality of life (QoL) in 183 patients with severe asthma treated with biologics or conventional therapy between April 2020 and May 2021.
  • The patients were assessed using the Questionnaire for Adult Korean Asthmatics (QLQAKA), Severe Asthma Questionnaire (SAQ), and EuroQoL-5Dimensions (EQ-5D) at baseline and 6 months.
  • The EQ-5D index of severe asthma was lower than that of other chronic diseases, indicating a worse QoL.
  • The scores for all questions of QLQAKA, except 'cough,' were lower in the severe asthma group than in the mild-to-moderate asthma group at baseline and 6 months (P < 0.05).
  • The QoL was worse in severe asthma than in mild-to-moderate asthma and other chronic diseases.
  • T2 biologics equally improved QoL in patients with severe asthma.
  • The study used data from the Cohort for Reality and Evolution of Adult Asthma in Korea and the Precision Medicine Intervention in Severe Asthma.
  • The findings suggest that biologics can be an effective treatment option for patients with severe asthma.

Statistics:

  • 183 patients with severe asthma were included in the study.
  • The patients were treated with biologics or conventional therapy between April 2020 and May 2021.
  • The EQ-5D index of severe asthma was 0.803, indicating a lower quality of life compared to other chronic diseases.
  • The scores for all questions of QLQAKA, except 'cough,' were lower in the severe asthma group than in the mild-to-moderate asthma group (P < 0.05).
  • The study found that T2 biologics equally improved QoL in patients with severe asthma.

Sources:

  • Effect of biologic therapies on quality of life in severe asthma: Findings from the PRISM study. World Allergy Organization Journal, 2024,17(9):100957. (World Allergy Organization Journal - https://www.journals.elsevier.com/world-allergy-organization-journal/)
  • NewsRx. Studies from Inje University College of Medicine Add New Findings in the Area of Biologics (Effect of biologic therapies on quality of life in severe asthma: Findings from the PRISM study). Respiratory Therapeutics Week. September 9, 2024; p 588.

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