Sign in Subscribe
Angiography

Association Between Hepatosteatosis and Coronary Artery Disease Revealed in Study

Strategic Insights

— 1 min read

Research conducted in Gaziantep, Turkiye, has shed light on the potential link between hepatosteatosis and coronary artery disease (CAD). The study, published in Clinical Radiology, aimed to evaluate the association between hepatosteatosis, epicardial adipose tissue (EAT), and paracardial adipose tissue (PAT) with CAD. The study analyzed 331 consecutive patients using coronary computed tomography angiography (CCTA) images, finding no correlation between the presence or severity of CAD and steatosis in either group. However, the proportion of patients with moderate and severe calcium scores was significantly higher in the steatosis group. Notably, EAT and PAT values were statistically significantly higher in the steatosis group than in the nonsteatosis group across both readers.

Key Takeaways:

  • The study aimed to evaluate the association between hepatosteatosis, EAT, and PAT with CAD in 331 consecutive patients.
  • No correlation was observed between the presence or severity of CAD and steatosis in either group.
  • The proportion of patients with moderate and severe calcium scores was significantly higher in the steatosis group (P = 0.016).
  • EAT and PAT values were statistically significantly higher in the steatosis group than in the nonsteatosis group across both readers.
  • The study suggests that hepatosteatosis may be associated with increased risk of CAD, although the exact mechanisms are unclear.
  • The researchers propose that EAT and PAT could serve as independent markers for determining the presence and severity of CAD.
  • The study highlights the importance of further research into the relationship between hepatosteatosis and CAD.
  • The findings have implications for the diagnosis and management of CAD in patients with hepatosteatosis.

Statistics:

  • 331 consecutive patients were participated in the study.
  • No correlation was observed between the presence or severity of CAD and steatosis in either group.
  • The proportion of patients with moderate and severe calcium scores was significantly higher in the steatosis group (P = 0.016).
  • EAT and PAT values were statistically significantly higher in the steatosis group than in the nonsteatosis group across both readers (P = 0.001).

Sources:

  • Hepatic and pericardial fat in coronary computed tomography angiography and its association with coronary artery disease. Clinical Radiology, 2025;91:107080.
  • O. Konukoglu et al., "Hepatic and pericardial fat in coronary computed tomography angiography and its association with coronary artery disease," Clinical Radiology, vol. 91, no. 10, pp. 107080, 2025.
  • NewsRx. Reports Outline Heart Disease Study Findings from Department of Radiology (Hepatic and pericardial fat in coronary computed tomography angiography and its association with coronary artery disease). Cardiovascular Week. October 20, 2025; p 109.

Read more