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Asthma

Depression Increases Risk of Asthma: New Study Provides Insights into Comorbidity

Strategic Insights

— 1 min read

Researchers from China have discovered a strong correlation between depression and asthma, with individuals suffering from depression being more likely to develop asthma. The study analyzed data from the 2005 to 2023 National Health and Nutrition Examination Survey, involving 38,127 participants. The findings suggest that depression increases the risk of asthma by 56% (OR = 1.56, 95% CI 1.35-1.80, P < 0.001).

Key Takeaways:

  • The study found a significant correlation between depression and asthma, with individuals with depression being more likely to develop asthma.
  • The analysis of 38,127 participants from the 2005 to 2023 National Health and Nutrition Examination Survey revealed a 56% increased risk of asthma in individuals with depression.
  • The study used weighted multivariate logistic regression to assess the depression-asthma association and controlled for age, sex, and other covariates.
  • Subgroup analyses were performed to explore risk variations, and Mendelian randomization analyses were conducted to examine the correlation and causality between depression and asthma.
  • The study concluded that further validation in large, prospective cohort studies is required to confirm the findings.
  • Additional authors of the study include Manli Ran, Wang Zhang, Minjian Wang, and Siying Luo.

Statistics:

  • The study involved 38,127 participants from the National Health and Nutrition Examination Survey (2005-2023).
  • The analysis revealed a 56% increased risk of asthma in individuals with depression (OR = 1.56, 95% CI 1.35-1.80, P < 0.001).
  • The study used weighted multivariate logistic regression to assess the depression-asthma association.

Sources:

  • Depression increases the risk of asthma: Evidence from a cross-sectional study and two-sample Mendelian randomization analysis. Medicine, 2025;104(40).
  • Lippincott Williams & Wilkins, Two Commerce Sq, 2001 Market St, Philadelphia, PA 19103, USA.
  • www.elsevier.com
  • www.journals.elsevier.com/medicine/

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