Postpartum Mood Episodes in Bipolar Disorders
Research at San Luigi Gonzaga University Hospital has shed new light on the relationship between postpartum mood episodes and bipolar disorder (BD) in women with a history of BD type I and II. The study, published in the International Journal of Bipolar Disorders, aimed to investigate the rates and clinical correlates of postpartum mood episodes in 248 women. The findings suggest that the postpartum period is a high-risk time for women with BD, particularly those with type II, and highlights the need for further studies to understand the predictors of recurrence.
Key Takeaways:
- The postpartum period is a recognized high-risk phase for maternal and infant health, particularly for women with bipolar disorder.
- The study found that 89 women with BD type I and 159 women with BD type II experienced postpartum mood episodes, with 27.4% of women with BD II experiencing episodes.
- The analysis revealed that women with BD II were more likely to experience postpartum mood episodes than those with BD I.
- The study also identified clinical correlates of postpartum mood episodes, including a history of previous mood episodes and comorbid psychiatric disorders.
- The researchers emphasized the need for further studies to validate and expand their findings, enhancing the understanding of mood recurrence risk during the postpartum period.
- Giorgia Porceddu, Psychiatric Unit, San Luigi Gonzaga University Hospital, led the research with a team that included Elena Teobaldi, Gabriele Di Salvo, Giuseppe Maina, and Gianluca Rosso.
- The International Journal of Bipolar Disorders published the study, highlighting the importance of international collaboration in advancing knowledge on bipolar disorders.
Statistics:
- 248 women with a history of at least one pregnancy and BD I or II participated in the study.
- 89 women with BD I experienced postpartum mood episodes compared to 159 women with BD II.
- Postpartum mood episodes occurred in 27.4% of women with BD II.
- 27.4% of women with BD II experienced postpartum mood episodes compared to 22.5% of women with BD I.
Sources:
- Postpartum mood episodes in bipolar I vs. II disorder: a retrospective observational analysis of clinical correlates. International Journal of Bipolar Disorders, 2025;13(1):27.
- San Luigi Gonzaga University Hospital, Regione Gonzole 10, Orbassano, Torino, 10043, Italy.
- Springer, One New York Plaza, Suite 4600, New York, Ny, United States.
- NewsRx LLC, 2025. Research Data from San Luigi Gonzaga University Hospital Update Understanding of Bipolar Disorders (Postpartum mood episodes in bipolar I vs. II disorder: a retrospective observational analysis of clinical correlates). Mental Health Weekly Digest. October 20, 2025; p 811.