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Diseases

Prevalence of Multiple Metabolic Diseases in Type 2 Diabetes Patients

Strategic Insights

— 2 min read

A recent study conducted by the Department of Endocrinology and Metabolism has shed light on the prevalence and clinical features of multiple metabolic diseases (MDs) in type 2 diabetes mellitus (T2DM) patients. The study, published in Diabetes, Metabolic Syndrome and Obesity, analyzed data from 9453 T2DM patients and found that the overall prevalence of MDs was a staggering 92.6%. The research revealed that the presence of MDs significantly increased the risk and severity of cardiovascular and kidney complications in T2DM patients.

Key Takeaways:

  • The study found that the overall prevalence of MDs in T2DM patients was 92.6%, with the prevalence remaining consistently high from 2003 to 2012 and increasing with age and diabetes duration (DD) except for MAFLD.
  • The prevalence of HLP was the highest among both males and females, while HUA had the lowest prevalence.
  • T2DM patients with MDs had a significantly higher prevalence of cardio-cerebrovascular events (CCBVEs) and chronic kidney disease (CKD) compared to those without MDs.
  • The presence of MDs in T2DM patients increased the risk and severity of cardiovascular and kidney complications.
  • The study concluded that early screening and intervention for MDs may help to reduce the risk of macrovascular and microvascular complications in T2DM.
  • The research involved a 10-year real-world study conducted from 2003 to 2012, analyzing data from 9453 T2DM patients.
  • The study highlighted the importance of addressing the burden of multiple metabolic diseases in T2DM patients to reduce the risk of cardiovascular and kidney complications.

Statistics:

  • Overall prevalence of MDs in T2DM patients: 92.6%
  • Prevalence of HPL in males: 64.3%
  • Prevalence of HPL in females: 67.1%
  • Prevalence of HUA in males: 17.1%
  • Prevalence of HUA in females: 20.5%
  • Prevalence of CCBVEs in patients with MDs: 35.1%
  • Prevalence of CKD in patients with MDs: 44.8%
  • Increase in risk of CCBVEs with MDs: 2.5 times
  • Increase in risk of CKD with MDs: 3.1 times

Sources:

  • The Burden of Multiple Metabolic Diseases and Their Impact on Cardiovascular and Kidney Complications in Type 2 Diabetes: A 10-Year Real-World Study. Diabetes, Metabolic Syndrome and Obesity, 2025, Volume 18(Issue 1):3717-3730. (Diabetes, Metabolic Syndrome and Obesity - http://www.dovepress.com/diabetes-metabolic-syndrome-and-obesity-targets-and-t)
  • NewsRx. Reports Outline Obesity and Diabetes Research from Department of Endocrinology and Metabolism (The Burden of Multiple Metabolic Diseases and Their Impact on Cardiovascular and Kidney Complications in Type 2 Diabetes: A 10-Year Real-World Study). Obesity & Diabetes Week. October 20, 2025; p 104.

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