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Medical care utilization

Pulmonary Embolism Treatment Outcomes Compared

Strategic Insights

— 1 min read

Researchers compared outcomes and healthcare resource utilization among patients treated with different methods for intermediate-risk pulmonary embolism (PE). According to the study, patients who received computer-assisted vacuum thrombectomy (CAVT) had shorter hospital stays, lower complication rates, and improved discharge outcomes compared to those treated with anticoagulation (AC), catheter-directed thrombolysis (CDL), or other mechanical thrombectomy (MT).

Key Takeaways:

  • Patients with intermediate-risk pulmonary embolism often experience extended hospitalizations and varied outcomes depending on the treatment modality.
  • The study compared outcomes and healthcare resource utilization among patients treated with anticoagulation (AC), catheter-directed thrombolysis (CDL), other mechanical thrombectomy (MT), or computer-assisted vacuum thrombectomy (CAVT) in the U.S.
  • CAVT had shorter length of stay (LOS) (4.6±3.23d) than AC (6.2±3.72d), P<0.001.
  • CAVT also had lower post-procedure intensive care unit days (PPICU), in-hospital mortality, and composite complications compared to other treatment modalities.
  • The results suggest that CAVT may be a more effective treatment option for intermediate-risk PE.
  • The study included 515 patients who were retrospectively identified from the Vizient Clinical Data Base between July 1, 2020, and September 30, 2023.
  • Propensity score matching (PSM) was used to equate groups 1:1 using demographics, payer, and hospital type.
  • The study's findings have been peer-reviewed and published in The American Journal of Cardiology.

Statistics:

  • 515 patients were included in the study, which was a retrospective analysis of data from the Vizient Clinical Data Base (July 1, 2020, to September 30, 2023).
  • CAVT had a shorter LOS (4.6±3.23d) compared to AC (6.2±3.72d), P<0.001.
  • CAVT had lower PPICU and in-hospital mortality rates compared to other treatment modalities.
  • The study found that CAVT reduced complications and improved discharge outcomes without increasing mortality.

Sources:

  • "Healthcare Resource Utilization and Outcomes in Intermediate-risk Pulmonary Embolism in the United States" (The American Journal of Cardiology, 2025)
  • NewsRx. Data on Pulmonary Embolism Detailed by Researchers at Department of Radiology (Healthcare Resource Utilization and Outcomes in Intermediate-risk Pulmonary Embolism in the United States). Respiratory Therapeutics Week. October 20, 2025; p 364.

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