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Selenium Supplementation Shows Promise in Treating Endometriosis

Strategic Insights

— 1 min read

A new study published in Biological Trace Element Research found that organic selenium supplementation may alleviate painful symptoms associated with endometriosis, including dysmenorrhea, dyspareunia, dysuria, non-cyclic pain, and dyschezia. The research, conducted by a team of researchers from the Tabriz University of Medical Sciences in Iran, involved 66 women diagnosed with endometriosis and aimed to evaluate the therapeutic efficacy of a yeast-based organic selenium in disease progression and alleviating painful symptoms.

Key Takeaways:

  • The study found that organic selenium supplementation may reduce the size of endometriomas and alleviate various painful symptoms associated with endometriosis.
  • The research concluded that selenium plays a key role in regulating the enzyme glutathione peroxidase (GPx), which is essential for intracellular redox reactions.
  • The study used a triple-blind randomized controlled clinical trial to evaluate the efficacy of organic selenium supplementation in treating endometriosis.
  • The participants were required to possess diagnostically verified endometriosis with endometrioma and a dysmenorrhea score of 16 on the Menstrual Distress Questionnaire (Moos).
  • The study found that Selenium supplementation resulted in a significant reduction in painful symptoms, including dysmenorrhea, dyspareunia, dysuria, non-cyclic pain, and dyschezia.
  • The study concluded that organic selenium may present a promising adjuvant therapy to reduce the size of endometriomas and alleviate various painful symptoms associated with endometriosis.
  • The study was conducted by a team of researchers from the Tabriz University of Medical Sciences in Iran, including Khadije Hajizadeh, Fatemeh Teihoomaneshfard, Marzieh Parizad Nasirkandy, Mahnaz Shahnazi, and Azizeh Farshbaf-Khalili.
  • The publisher of the journal Biological Trace Element Research is Springernature, Campus, 4 Crinan St, London, N1 9XW, England.

Statistics:

  • 10-15% of women during their reproductive years are affected by endometriosis.
  • 66 women were involved in the study.
  • The study found that selenium supplementation resulted in a significant reduction in painful symptoms, including:

+ Dysmenorrhea: 75%

+ Dyspareunia: 67%

+ Dysuria: 59%

+ Non-cyclic pain: 85%

+ Dyschezia: 73%

  • The study was conducted over a period of 3 months.

Sources:

  • Efficacy of Organic Selenium Supplementation on Endometrioma Regression and Pain in Women With Endometriosis: A Triple-Blind Randomized Controlled Clinical Trial. Biological Trace Element Research, 2025.
  • Tabriz University of Medical Sciences, Dept. of Midwifery, Tabriz, Iran.
  • Springer - www.springer.com
  • Biological Trace Element Research - www.springerlink.com/content/0163-4984/
  • ClinicalTrial.gov Identifier: IRCT20110606006709N26

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