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Body mass index

Association between TyG-BMI and Cardiometabolic Complications in Chronic Liver Disease

Strategic Insights

— 1 min read

New research conducted by researchers at the First Affiliated Hospital in Ningbo, China, has shed light on the relationship between the triglyceride-glucose-body mass index (TyG-BMI) and cardiometabolic complications in patients with chronic liver disease (CLD). The study, published in the European Journal of Medical Research, aimed to investigate whether the TyG-BMI and its trajectory are associated with cardiometabolic comorbidities, such as Cardiovascular-Kidney-Metabolic syndrome (CKM), in CLD patients. The research found that high baseline TyG-BMI values were associated with an increased risk of CKM syndrome and other cardiometabolic diseases.

Key Takeaways:

  • The study found that high baseline TyG-BMI values were associated with an increased risk of CKM syndrome and other cardiometabolic diseases in CLD patients.
  • The research used data from the China Health and Retirement Longitudinal Study (CHARLS) from 2011 to 2020 and included 765 participants in the CKM cohort.
  • The study found that an increased TyG-BMI was associated with a higher risk of cardiometabolic complications, with a hazards ratio of 2.404 (1.889-3.060) for high baseline TyG-BMI values.
  • The research concluded that monitoring TyG-BMI might improve the prognosis of patients with CLD.
  • The study highlights the importance of considering the TyG-BMI in the management of CLD patients, particularly in the context of cardiometabolic comorbidities.

Statistics:

  • The study included 765 participants in the CKM cohort, of whom 426 (55.7%) were male and 339 (44.3%) were female.
  • High baseline TyG-BMI values were associated with an increased risk of CKM syndrome and other cardiometabolic diseases.
  • The hazards ratio for high baseline TyG-BMI values was 2.404 (1.889-3.060).
  • The study used data from the China Health and Retirement Longitudinal Study (CHARLS) from 2011 to 2020.
  • The research found that an increased TyG-BMI was associated with a higher risk of cardiometabolic complications.

Sources:

  • European Journal of Medical Research (2025;30(1):935)
  • Bmc (Euroepan Journal of Medical Research can be contacted at: Bmc, Campus, 4 Crinan St, London N1 9XW, England)
  • China Health and Retirement Longitudinal Study (CHARLS)

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