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Atherosclerosis

Epicardial Adiposity and STEMI Outcomes

Strategic Insights

— 1 min read

Research from Bahcesehir University, published in Clinical Physiology and Functional Imaging, has found no correlation between epicardial adiposity and mortality or major adverse cardiac and cerebrovascular events (MACCE) in ST-segment elevation myocardial infarction (STEMI) patients. The study, which evaluated 138 STEMI patients, found significant differences in age, weight, body mass index (BMI), thrombolysis in myocardial infarction (TIMI) scores, and number of affected vessels across tertiles of epicardial adiposity thickness, but not in mortality or MACCE outcomes.

Key Takeaways:

  • The study found that epicardial adiposity thickness ranged from 1.5 to 11 mm, with an average of 3.91 ± 1.42 mm in STEMI patients.
  • The patients were divided into tertiles by epicardial adiposity thickness, showing significant differences in age, weight, BMI, TIMI scores, and number of affected vessels.
  • No correlation was found between epicardial adiposity thickness and mortality or MACCE in STEMI patients, highlighting the need for validation in long-term studies.
  • The study included 124 males and 14 females, with an average age of 55.14 ± 12.83 years, predominantly with diabetes (22.5%), hypertension (38.4%), hyperlipidemia (37%), metabolic syndrome (32.6%), and family history of cardiovascular disease (47.1%).
  • The researchers concluded that epicardial adiposity may have a complex relationship with cardiovascular disease and that further studies are needed to determine its prognostic value.

Statistics:

  • The study included 138 STEMI patients, with 124 males and 14 females.
  • The average age of the patients was 55.14 ± 12.83 years, with an age range of 26-82 years.
  • The mean epicardial adiposity thickness was 3.91 ± 1.42 mm, with a range of 1.5-11 mm.
  • The patients had a high prevalence of comorbidities, including diabetes (22.5%), hypertension (38.4%), hyperlipidemia (37%), metabolic syndrome (32.6%), and family history of cardiovascular disease (47.1%).
  • The study found no correlation between epicardial adiposity thickness and mortality (7.2%) or MACCE (13.8%) in STEMI patients.

Sources:

  • The impact of epicardial adiposity on STEMI outcomes: Insights from a prospective cohort. Clinical Physiology and Functional Imaging, 2025;45(6).
  • NewsRx. Investigators at Bahcesehir University Report New Data on Obesity and Diabetes (The impact of epicardial adiposity on STEMI outcomes: Insights from a prospective cohort). Obesity & Diabetes Week. November 3, 2025; p 55.

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