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Factors Influencing Treatment Outcomes of Drug-Sensitive Tuberculosis Patients in Indonesia

Strategic Insights

— 1 min read

Research conducted by Diponegoro University has shed light on the characteristics of tuberculosis (TB) patients at R.A. Kartini Hospital and the factors that influence the results of pulmonary TB therapy. The study's findings highlight the importance of age, employment status, and TB-HIV co-infection in determining treatment outcomes. With a high TB treatment success rate of 87% in Central Java Province, researchers emphasize the need for targeted interventions to improve treatment outcomes, particularly for working individuals and those with TB-HIV co-infection.

Key Takeaways:

  • The study aimed to provide an overview of TB patients at R.A. Kartini Hospital and identify factors influencing treatment outcomes.
  • The average age of subjects was 39.26 ± 19.36, with the majority being male (58.5%).
  • Data showed that 58.1% of subjects had jobs, and the majority had no history of diabetes mellitus (DM) or human immunodeficiency virus (HIV) (86.6% and 96.7%, respectively).
  • All subjects received TB treatment; most recovered (76.4%).
  • Bivariate logistic regression analysis demonstrated that age was significantly related to TB treatment outcomes, with an odds ratio (OR) of 1.033 (p = 0.000).
  • Employment status was also significantly related to TB treatment outcomes, with working subjects 2.261 times more likely to experience suboptimal treatment outcomes (p = 0.013).
  • TB-HIV co-infection was significantly related to TB treatment outcomes after adjusting for age with multivariate logistic regression analysis.

Statistics:

  • TB treatment success rate in Central Java Province: 87%
  • Average age of subjects: 39.26 ± 19.36
  • Male subjects: 58.5%
  • Subjects employed: 58.1%
  • Subjects with a history of diabetes mellitus (DM): 13.4%
  • Subjects with a history of human immunodeficiency virus (HIV): 3.3%
  • TB treatment recovery rate: 76.4%

Sources:

  • Factors Influencing Treatment Outcomes of Drug-sensitive Tuberculosis Patients: Study in R.A. Kartini Hospital, Jepara, Indonesia. Jurnal Kedokteran Diponegoro, 2025, 14(5):254-261
  • NewsRx. Data from Diponegoro University Update Knowledge in HIV/AIDS (Factors Influencing Treatment Outcomes of Drug-sensitive Tuberculosis Patients: Study in R.A. Kartini Hospital, Jepara, Indonesia). AIDS Weekly. November 3, 2025; p 13.

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