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Telemedicine Reduces Major Adverse Cardiac Events in Post-PCI Patients with Coronary Heart Disease

Strategic Insights

— 2 min read

A significant reduction in major adverse cardiac events (MACCE) among patients with coronary heart disease (CHD) was observed in a recent randomized controlled trial conducted in China. The study's findings suggest that telemedical interventional management can enhance clinical outcomes and improve risk factor control among patients with CHD who have undergone percutaneous coronary intervention (PCI). The researchers from the First Affiliated Hospital of University of Science and Technology China (USTC) found that the telemedicine platform, which provided personalized health education, medication reminders, vital sign monitoring, and artificial intelligence-assisted consultations, resulted in a 3.5% rate of MACCE in the intervention group compared to 5.3% in the control group.

Key Takeaways:

  • The telemedicine platform demonstrated a significant reduction in MACCE among patients with CHD following PCI, with a 28% decrease in the intervention group compared to the control group.
  • The primary outcome of the study was the composite incidence of MACCE, including cardiac death, myocardial infarction, stroke, or target vessel revascularization, at one year.
  • The intervention group exhibited improved control over systolic blood pressure and diastolic blood pressure, with a 4.7% and 3.1% decrease in mean blood pressure, respectively.
  • Higher medication adherence to aspirin (87.8%) and angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, or angiotensin receptor-neprilysin inhibitors (48.1%) was observed in the intervention group compared to the control group.
  • There was a notable reduction in alcohol consumption among participants in the intervention group (11.7% vs 16.5%), alongside a trend towards decreased smoking rates (11.2% vs 14.0%).
  • Long-term care strategies and secondary prevention efforts can be strengthened by the implementation of telemedicine platforms in clinical practice.

Statistics:

  • 2086 patients with post-PCI CHD were randomly assigned to receive either telemedical management combined with usual care (n=1040) or usual care alone (n=1046).
  • The control group received follow-up phone calls from healthcare providers at 1, 3, 6, and 12 months after discharge, while the remote patient management group benefited from multicomponent interventions delivered through a telemedicine platform, alongside usual care.
  • At one-year follow-up, the intervention group demonstrated a 36% reduction in MACCE compared to the control group (36/1040 vs 55/1046, P=.04).
  • Lower rates of cardiac death (1.0% vs 2.3%, P=.02) and myocardial infarction (0.8% vs 1.8%, P=.03) were observed in the intervention group.
  • Bleeding events classified as BARC 3-5 were less frequent in the intervention group (0.6% vs 1.6%, P=.03).

Sources:

  • "Efficacy of Telemedical Interventional Management in Patients with Coronary Heart Disease Undergoing Percutaneous Coronary Intervention: Randomized Controlled Trial." Journal of Medical Internet Research, 2025;27.
  • First Affiliated Hospital of University of Science and Technology China (USTC).
  • Jmir Publications, Inc.
  • University of Science and Technology of China, No. 17, Lujiang Road, Hefei, 230001, China.

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