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COVID-19

Adapting COVID-19 Guidelines for Therapeutics in Argentina

Strategic Insights

— 1 min read

A new research study published in the Journal of Clinical Epidemiology has demonstrated the effectiveness of a tailored adaptation process in translating and adapting the World Health Organization (WHO) living guidelines for COVID-19 recommendations for therapeutics in Argentina. The study, conducted by McMaster University, found that the adapted recommendations were accepted by the guideline development group (GDG) due to their transparency, efficiency, and flexibility. The research was conducted in partnership with the MAGIC Evidence Ecosystem Foundation and used a prototype tool to facilitate the adaptation process.

Key Takeaways:

  • The study assessed the perceptions of the GDG regarding the adaptation process of the WHO living guidelines for COVID-19.
  • The GDG adapted four recommendations, with two modified in direction or strength and one de novo.
  • The survey showed that most GDG members found the training session and prepanel meeting survey facilitated adaptation.
  • Focus groups and interviews revealed that GDG valued the process's flexibility and time optimization.
  • The study demonstrated the potential of the tailored adaptation process in balancing methodological rigor with efficiency and flexibility.
  • The research has been peer-reviewed and published in the Journal of Clinical Epidemiology.

Statistics:

  • 89% of GDG members found the training session facilitated adaptation.
  • 100% of GDG members found the prepanel meeting survey facilitated adaptation.
  • 4 recommendations were adapted by the GDG, with 2 modified in direction or strength and 1 de novo.
  • The study used a prototype tool to facilitate the adaptation process.
  • The research was conducted from December 2022 to June 2023.

Sources:

  • Adapting World Health Organization COVID-19 living guidelines balancing methodological rigor with efficiency and flexibility: a case study from Argentina. Journal of Clinical Epidemiology, 2025;184:111823.
  • McMaster University. [1]
  • Journal of Clinical Epidemiology. [1]
  • MAGIC Evidence Ecosystem Foundation. [1]
  • Elsevier Science Inc. [1]
  • Carlos Zaror, Dept. of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.

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