Biosynthesis of Non-toxic TiO2 Nanoparticles Using Polysaccharide Rich Marine Algae

Researchers from the University of Chile have made a significant breakthrough in the development of non-toxic TiO2 nanoparticles using polysaccharide-rich marine algae. The study, recently published in the journal Colloids and Surfaces A-physicochemical and Engineering Aspects, demonstrates the potential of using environmentally friendly procedures to produce nanoparticles with combined antibacterial and antioxidant properties. The research team, led by Franck Quero, successfully synthesized TiO2 nanoparticles using a polysaccharide-rich algal extract, which acted as both a bio-reduction and capping agent.

Key Takeaways:

  • The study demonstrated the potential of using environmentally friendly procedures to produce nanoparticles with antibacterial and antioxidant properties.
  • The researchers used a polysaccharide-rich algal extract to synthesize TiO2 nanoparticles, which showed anti-oxidant properties and inhibited the formation of biofilms.
  • The study confirmed the presence of algal functional groups onto the surface of the TiO2 NPs using ultraviolet-visible diffuse reflectance spectroscopy and FTIR.
  • Powder XRD analysis confirmed the polycrystalline nature of the TiO2 NPs having tetragonal crystal structure.
  • Field emission scanning and transmission electron microscopy revealed the formation of agglomerated non-spherical structures.
  • The obtained TiO2 NPs inhibited the metabolic respiration of A. baumannii and K. pneumoniae at 250 μg/mL.
  • The study suggested that the biosynthesized TiO2 NPs had low toxicity against A. franciscana and had potential for clinical use.

Statistics:

  • The researchers synthesized TiO2 nanoparticles using a polysaccharide-rich algal extract.
  • The study demonstrated the inhibition of biofilm production by A. baumannii and K. pneumoniae at concentrations of 250 μg/mL.
  • The nanoparticles showed anti-oxidant properties and inhibited the formation of biofilms.
  • The study confirmed the presence of algal functional groups onto the surface of the TiO2 NPs using ultraviolet-visible diffuse reflectance spectroscopy and FTIR.
  • Powder XRD analysis revealed the polycrystalline nature of the TiO2 NPs having tetragonal crystal structure.

Sources:

  • NewsRx. Researchers from University of Chile Report on Findings in Nanoparticles (Biosynthesis of Non-toxic Tio 2 Nanoparticles Using Polysaccharide Rich Marine Algae Caulerpa Racemose for Inhibition of Biofilm-producing Bacteria). Medical Imaging Week. May 31, 2025; p 1079.
  • Colloids and Surfaces A-physicochemical and Engineering Aspects. Biosynthesis of Non-toxic Tio 2 Nanoparticles Using Polysaccharide Rich Marine Algae Caulerpa Racemose for Inhibition of Biofilm-producing Bacteria. 2025;713.