Breakthrough in AIDS Research: Juven Shows Promise in Fighting Muscle Wasting

Scientists at the World AIDS Conference in Geneva have unveiled the results of a two-year study that shows dramatic improvements in muscle wasting in AIDS patients who took a nonprescription amino acid formula called Juven. The research, led by Dr. Robert Clark, M.D., Director of Ambulatory HIV Services at Nassau County Medical Center, demonstrates that Juven can help patients stop muscle loss and even restore lost muscle mass without the use of steroids or growth hormone.

The clinical study involved 200 AIDS patients who had lost at least five percent of their body weight over the past two months. Patients taking Juven gained an average of 6.5 pounds over eight weeks, with 5.5 pounds of it being muscle, compared to the placebo group, which continued to lose muscle at an average of 1.5 pounds during the same period.

Key Takeaways:

  • Juven, a nonprescription amino acid formula, shows promise in fighting muscle wasting in AIDS patients, with an average gain of 6.5 pounds, including 5.5 pounds of muscle, over eight weeks.
  • The clinical study, conducted by Dr. Robert Clark, M.D., involved 200 AIDS patients, comparing those taking Juven to a placebo group.
  • Patients taking Juven experienced significant muscle growth and restoration, while the placebo group continued to lose muscle.
  • The cost of Juven is significantly less than current therapies, with a 15-day supply available for $89.
  • The FDA classifies the three main ingredients in Juven (HMB, L-glutamine, and L-arginine) as natural, nutritional products.
  • The key ingredient in Juven, beta-hydroxy-beta-methylbutyrate (HMB), has been extensively documented for its muscle-building properties.
  • HMB is produced in small amounts by the human body as it breaks down the amino acid leucine, and it prevents muscle breakdown, making it a powerful synergistic effect.

Statistics:

  • 200 AIDS patients participated in the clinical study.
  • The average gain in weight for patients taking Juven was 6.5 pounds over eight weeks.
  • 5.5 pounds of the weight gain for patients taking Juven was muscle mass.
  • 1.5 pounds of muscle was lost by the placebo group over the same period.
  • The cost of Juven is $89 for a 15-day supply.
  • The wholesale price of growth hormone is $1,750 per week.
  • 30% muscle loss is almost always fatal in cases of illness or disease.

Sources:

  • PRNewswire, "MTI BioTech's Juven Shows Dramatic Results for AIDS Patients Suffering Muscle Wasting" (June 29, 1998)
  • MTI BioTech, Inc.
  • Iowa State University
  • World AIDS Conference
  • Dr. Robert Clark, M.D.
  • Dr. Steven L. Nissen, D.V.M., Ph.D.