Breakthroughs in Gastric Cancer Immunotherapy: Latest Research from Shanghai University of Traditional Chinese Medicine
A groundbreaking study published in Technology in Cancer Research & Treatment has made significant strides in the treatment of gastric cancer, with researchers from Shanghai University of Traditional Chinese Medicine exploring innovative immunotherapy approaches.
Key Takeaways:
- Gastric cancer is one of the most common gastrointestinal tract cancers worldwide, with high incidence and mortality rates and poor prognosis.
- Multidisciplinary comprehensive therapies consisting of surgery, chemotherapy, radiotherapy, and targeted therapy have made progress in GC treatment, but a satisfactory curative effect still cannot be achieved in many circumstances.
- The 5-year survival of patients with GC remains to be very low, with about 75% of patients diagnosed in the advanced stage and missing the opportunity of surgical resection.
- Immunotherapy has gradually become a new essential treatment for GC, with the US FDA and China FDA approving a variety of immune-related drugs.
- The research reviewed recent developments in nonspecific enhancer therapy, adoptive immunocell therapy, tumor vaccine therapy, oncolytic virus therapy, and immune checkpoint inhibitor therapy for the treatment of GC.
- Shanghai University of Traditional Chinese Medicine has made significant contributions to the field of oncology, with researchers like Ningning Liu MD and Mingyu Sun MD conducting pioneering work in cancer gene therapy.
Statistics:
- 75% of patients with gastric cancer are diagnosed in the advanced stage, missing the opportunity of surgical resection.
- The 5-year survival of patients with GC remains to be very low.
- The US FDA and China FDA have approved various immune-related drugs for the treatment of GC, with good efficacy reported.
Sources:
- Research Progress of Immunotherapy for Gastric Cancer. Technology in Cancer Research & Treatment, 2023,22.
- https://doi-org.sdpl.idm.oclc.org/10.1177/15330338221150555
- Shanghai University of Traditional Chinese Medicine.
- Zhipeng Zhang MD, Key Laboratory of Liver and Kidney Diseases (Ministry of Education), Institute of Liver Disease, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.