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COVID-19

COVID-19 Associated with Higher Burden of Cardiovascular Morbidity and Mortality

Strategic Insights

— 1 min read

Current study results on COVID-19 have shown a strong association with a higher burden of cardiovascular morbidity and mortality. Researchers at Texas Tech University Health Sciences Center School of Medicine conducted a population-based cohort study to investigate the association between COVID-19 and mortality in hospitalizations with coronary artery bypass graft (CABG). The study found that CABG hospitalizations with COVID-19 had higher rates of comorbidity, invasive mechanical ventilation, myocardial infarction, congestive heart failure, and acute kidney injury compared to those without COVID-19.

Key Takeaways:

  • The study found a strong association between COVID-19 and increased length of stay in hospitalizations with CABG, even after the pandemic's conclusion.
  • CABG hospitalizations with COVID-19 had higher comorbidity indices (2.01 ± 1.65 vs 1.65 ± 1.61) and more frequent need for invasive mechanical ventilation (12.8% vs 8.5%).
  • COVID-19 was associated with higher rates of myocardial infarction (65.0% vs 45.6%), congestive heart failure (53.4% vs 40.1%), and acute kidney injury (35.6% vs 24.3%).
  • The study included 47,501 hospitalizations with a procedure code for CABG, of which 509 (1.1%) had COVID-19.
  • The research concluded that COVID-19 has remained strongly associated with increased length of stay in hospitalizations with CABG.

Statistics:

  • 47,501 total hospitalizations with a procedure code for CABG were identified in the study.
  • 509 (1.1%) of these hospitalizations had COVID-19.
  • CABG hospitalizations with COVID-19 had higher comorbidity indices:

+ 2.01 ± 1.65

+ 1.65 ± 1.61 (CABG hospitalizations without COVID-19)

  • CABG hospitalizations with COVID-19 had higher rates of myocardial infarction:

+ 65.0%

+ 45.6% (CABG hospitalizations without COVID-19)

  • CABG hospitalizations with COVID-19 had higher rates of congestive heart failure:

+ 53.4%

+ 40.1% (CABG hospitalizations without COVID-19)

  • CABG hospitalizations with COVID-19 had higher rates of acute kidney injury:

+ 35.6%

+ 24.3% (CABG hospitalizations without COVID-19)

Sources:

  • NewsRx. Studies from Texas Tech University Health Sciences Center School of Medicine Have Provided New Information about COVID-19 (The Association of COVID-19 and Mortality in Hospitalizations With Coronary Artery Bypass Graft). Heart Disease Weekly. October 19, 2025; p 200.
  • The Association of COVID-19 and Mortality in Hospitalizations With Coronary Artery Bypass Graft. Journal of the Society for Cardiovascular Angiography & Interventions, 2025;4(8):103605.

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