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COVID-19

COVID-19 Study Reveals Higher Mortality in First Two Waves of Pandemic in Mexico

Strategic Insights

— 2 min read

A study published in The Journal of Infection in Developing Countries has shed light on the clinical severity and risk factors associated with mortality in patients hospitalized with COVID-19 in Mexico City. The research revealed that the first and second epidemiological waves of the pandemic presented a unique behavior in terms of clinical presentation, severity, and transmissibility, with higher mortality rates observed in these periods. The study's findings highlight the importance of monitoring and addressing chronic diseases such as diabetes mellitus and arterial hypertension, which were associated with a higher risk of death in patients hospitalized with COVID-19.

Key Takeaways:

  • The study included 1,752 patients hospitalized with COVID-19, with an average age of 54 years and at least one comorbidity, such as diabetes mellitus (33.3%), systemic arterial hypertension (28.3%), chronic kidney disease (8.67%), chronic obstructive pulmonary disease (1.35%), and cancer (4.82%).
  • The average length of hospital stay was 11.93 days, and general mortality was 29%, with higher mortality rates observed in the first and second waves of COVID-19.
  • Admission to the intensive care unit and mechanical ventilation were required in 21.6% and 5%, respectively, highlighting the severity of the disease in these patients.
  • Chronic diseases such as diabetes mellitus and arterial hypertension were associated with a higher risk of death in patients hospitalized with COVID-19.
  • The study's findings have implications for public health policy and clinical practice in Mexico and beyond, emphasizing the need for targeted interventions to address chronic disease management and reduce mortality rates.

Statistics:

  • 1,752 patients were included in the study, with an average age of 54 years.
  • 33.3% of patients had diabetes mellitus, 28.3% had systemic arterial hypertension, and 8.67% had chronic kidney disease.
  • The average length of hospital stay was 11.93 days.
  • General mortality was 29%, with higher mortality rates observed in the first and second waves of COVID-19.
  • 21.6% of patients required admission to the intensive care unit, and 5% required mechanical ventilation.

Sources:

  • Clinical Behavior of Covid-19 In a Reference Public Hospital In Mexico City During Sars-cov-2 Epidemiological Waves. The Journal of Infection in Developing Countries, 2025;19(01):17-21.
  • NewsRx. Reports Outline COVID-19 Study Findings from General Hospital of Mexico (Clinical Behavior of Covid-19 In a Reference Public Hospital In Mexico City During Sars-cov-2 Epidemiological Waves). Medical Letter on the CDC & FDA. May 18, 2025; p 212.

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