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Genetic research

Cyprus Institute of Neurology and Genetics Launches Two Research Programs to Improve Cancer Classification

Strategic Insights

— 1 min read

The Cyprus Institute of Neurology and Genetics (CING) has initiated two new research projects, BcRAVE and OVATION, aimed at enhancing the classification of genetic variants linked to breast and ovarian cancer. These projects, with a combined funding of £329,000, will run for two years under the EU-backed Cohesion Policy Programme Thaleia 2021-2027, coordinated by the Research and Innovation Foundation (RIF). The ultimate goal is to provide more accurate counselling and personalized treatment options for patients.

Key Takeaways:

  • BcRAVE, a £129,000 funded project, focuses on developing biostatistical tools for classifying genetic variants of uncertain clinical significance (VUS) in breast cancer genes, utilizing data from case-control studies and synthetic datasets.
  • OVATION, a £200,000 funded initiative, applies artificial intelligence and machine learning to VUS classification in ovarian cancer, incorporating tumour characteristics and biological data.
  • Both projects are part of a broader effort to integrate genetic data into clinical care and strengthen Cyprus' contribution to international collaborations in medical genetics.
  • The projects aim to increase statistical power and support decision-making in genetic counselling, enabling more precise diagnoses and tailored treatment approaches.
  • BcRAVE is part of the "Horizon Europe 2nd Chance MSCA" scheme, demonstrating the program's commitment to advancing research in the medical genetics field.

Statistics:

  • £329,000: The combined funding for the two research projects over two years.
  • £129,000: The funding allocated to BcRAVE, a project focused on developing biostatistical tools for breast cancer gene classification.
  • £200,000: The funding allocated to OVATION, an initiative utilizing artificial intelligence and machine learning for ovarian cancer classification.
  • 2 years: The duration of the projects under the EU-backed Cohesion Policy Programme Thaleia 2021-2027.
  • 2 programs: The number of research initiatives launched by CING to improve cancer classification and genetic counselling.

Sources:

  • Cyprus Institute of Neurology and Genetics press release

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