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Agriculture

Detection of Multidrug-Resistant Bacteria in Egyptian Poultry Farm

Strategic Insights

— 1 min read

Researchers from Mansoura University, in collaboration with Japan Agency for Medical Research and Development, have identified a multidrug-resistant (MDR) Escherichia coli strain in a poultry farm in Egypt. This strain, designated as M2-13-1, was found to be resistant to multiple antibiotics, including meropenem and doripenem. The study, published in the journal Microorganisms, highlights the importance of monitoring and controlling the spread of antibiotic-resistant bacteria in agriculture.

Key Takeaways:

  • The M2-13-1 strain was identified in a fecal swab from a poultry farm in Egypt in 2019.
  • The strain is classified as ST167, serotype O101:H5, phylogroup A, and shows an MDR phenotype.
  • The strain harbors genes that impart resistance to sulfonamides, trimethoprim, beta-lactams, aminoglycosides, tetracycline, and chloramphenicol.
  • The strain is susceptible to aztreonam, colistin, fosfomycin, and tigecycline.
  • The genetic context surrounding the strain's resistance genes includes a 49,816 bp IncX3 plasmid and a 113,285 bp IncFII: IncFIB plasmid.
  • The study highlights the importance of monitoring and controlling the spread of antibiotic-resistant bacteria in agriculture.

Statistics:

  • The M2-13-1 strain has a chromosome of 4,738,278 bp and encodes 4557 predicted genes.
  • The G + C content of the strain's chromosome is 50.8%.
  • The strain has a minimum inhibitory concentration (MIC) of 64 mg/L for both meropenem and doripenem.
  • The strain harbors both and genes on separate plasmids.

Sources:

  • Findings from Mansoura University Provides New Data on Poultry Farming (Detection and Genomic Characteristics of NDM-19- and QnrS11-Producing O101:H5 Escherichia coli Strain Phylogroup A: ST167 from a Poultry Farm in Egypt). Health & Medicine Week. September 19, 2025; p 1018.
  • Microorganisms. 2025;13(8):1769. Detection and Genomic Characteristics of NDM-19- and QnrS11-Producing O101:H5 Escherichia coli Strain Phylogroup A: ST167 from a Poultry Farm in Egypt.

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