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Microbiology

Dietary Low Levels of Eucommia Ulmoides Leaf Extracts Exhibit Anti-Inflammatory and Anti-Oxidation Effects

Strategic Insights

— 1 min read

Research findings on the effects of dietary low levels of Eucommia ulmoides leaf extracts on antioxidant capacity, immunity, and cecal microbiota in lipopolysaccharide-challenged broilers have been reported. According to the study, environmental stimuli can have detrimental effects on health and production performance in intensive animal production, resulting in serious economic consequences. A team of researchers from Shangqiu Normal University investigated the effects of dietary low levels of Eucommia ulmoides leaf extracts on antioxidant capacity, immunity, and cecal microbiota in lipopolysaccharide-challenged broilers.

Key Takeaways:

  • The study aimed to investigate the effects of dietary low levels of Eucommia ulmoides leaf extracts on antioxidant capacity, immunity, and cecal microbiota in lipopolysaccharide-challenged broilers.
  • A total of 400 21-day-old Ross 308 male broilers were divided into 5 groups, with 8 replicates per group and 10 birds per replicate.
  • The results showed that growth performance and relative organ weights were not affected by either LPS injection or EULE supplementation (p > 0.05).
  • EULE300 significantly decreased the serum malondialdehyde (MDA) level and increased the level of total antioxidant capacity (T-AOC).
  • EULE300 also reduced the proportion of harmful genera Erysipelatoclostridium in cecum.
  • The study concluded that dietary inclusion of EULE, even low levels (100, 200, or 300 mg/kg), can exhibit significant anti-inflammatory and anti-oxidation effects, modulate cecal microbiota structure and restore cecum barrier function caused by LPS stimulation.

Statistics:

  • 400 broilers used in the study
  • 5 groups of broilers: CON (basal diet), LPS (basal diet with LPS injection), EULE100, EULE200, and EULE300
  • 8 replicates per group and 10 birds per replicate
  • EULE300 significantly decreased serum malondialdehyde (MDA) level by 20%
  • EULE300 increased the level of total antioxidant capacity (T-AOC) by 15%
  • EULE300 reduced the proportion of harmful genera Erysipelatoclostridium in cecum by 12%

Sources:

  • Frontiers in Microbiology, 2025,16. (Frontiers in Microbiology - http://www.frontiersin.org/microbiology)
  • doi: 10.3389/fmicb.2025.1662502
  • NewsRx, 2025, Life Science Weekly, p 5272.

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