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Genetic research

Genetic Diversity and Single Nucleotide Polymorphism of Growth Hormones Receptor Gene in Different Goats Breeds

Strategic Insights

— 1 min read

A new study conducted at the University of Benin has shed light on the economic significance of genetic diversity in goats, specifically focusing on the growth hormone receptor gene. The investigation aimed to identify genetic diversity and single nucleotide polymorphism (SNPs) of the growth hormone receptor gene in various goat breeds. The study found that crossbred animals exhibited the highest number of SNPs, with some of these identified SNPs having associations with productive performance. Furthermore, the phylogenetic tree of the goats' GHR showed two clusters with different ancestral identities, and the genetic distances revealed close relationships between certain breeds.

Key Takeaways:

  • The study identified 20 SNPs in the growth hormone receptor gene, with 14 due to substitution and 6 due to deletion.
  • Crossbred animals (West African Long-legged x Red Sokoto) were found to have the highest number of SNPs.
  • The phylogenetic tree of the goats' GHR showed two clusters, with the first cluster having 88% ancestral identity and the second having 78% ancestral identity.
  • Maradi, WAD, and Red Sokoto in the first clusters had the highest similarity, while the genetic distances showed the closest distance to Maradi and Red Sokoto, Maradi and WAD, and WAD and Red Sokoto.
  • The study concluded that the investigations successfully identified economically important traits in goats, their phylogenetic relationship, and genetic distances.
  • The research recommended further associations' studies on economically important traits for marker-assisted selection and improvement in livestock productivity.
  • The study was published in the Journal of the Saudi Society of Agricultural Sciences, 2025, 24(3): 1-8.

Statistics:

  • 20 SNPs were identified in the growth hormone receptor gene.
  • 14 SNPs were due to substitution.
  • 6 SNPs were due to deletion.
  • 88% ancestral identity was observed in the first cluster of the phylogenetic tree.
  • 78% ancestral identity was observed in the second cluster of the phylogenetic tree.
  • Maradi, WAD, and Red Sokoto had the highest similarity (88%).
  • The closest genetic distance was observed between Maradi and Red Sokoto (0.0000), Maradi and WAD (0.0000), and WAD and Red Sokoto (0.0000).

Sources:

  • Genetic diversity and single nucleotide polymorphism of growth hormones receptor gene in different goats breeds. Journal of the Saudi Society of Agricultural Sciences, 2025,24(3):1-8.
  • NewsRx. Researchers at University of Benin Release New Study Findings on Anterior Pituitary Hormones (Genetic diversity and single nucleotide polymorphism of growth hormones receptor gene in different goats breeds). Life Science Weekly. June 10, 2025; p 5258.

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