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Grand Multiparity Linked to Type 2 Diabetes in Filipino American Women

Strategic Insights

— 1 min read

Recent research has uncovered a significant association between grand multiparity and an increased risk of type 2 diabetes in Filipino American women. A study conducted at the University of California San Diego found that women with six or more children were three times more likely to develop type 2 diabetes, independent of other risk factors such as visceral fat, adiponectin, and family history of diabetes. The study's findings highlight the importance of considering reproductive history in the assessment and prevention of type 2 diabetes.

Key Takeaways:

  • Grand multiparity, defined as six or more children, was associated with a threefold higher odds of type 2 diabetes in Filipino American women.
  • The association remained significant after adjusting for adiponectin, visceral fat, family history of diabetes, age, education, hypertension, and estrogen use.
  • Women with grand multiparity were more likely to have hypertension, higher visceral adipose tissue, and lower adiponectin concentration compared to women with lower parity.
  • The study's findings suggest that reproductive history may be an important factor in the development of type 2 diabetes, independent of other risk factors.
  • The association between grand multiparity and type 2 diabetes was observed in a ethnically homogenous population, highlighting the need for further research in diverse populations.
  • The study's sample size was relatively small, with 152 women participating in the study.

Statistics:

  • 25% of women with low parity (1-2 births) had type 2 diabetes.
  • 30.3% of women with medium parity (3-5 births) had type 2 diabetes.
  • 50% of women with grand multiparity (6-12 births) had type 2 diabetes.
  • Women with grand multiparity were significantly older (62 vs. 57 years) compared to women with lower parity.
  • Women with grand multiparity had lower college completion (22 vs. 58%) and more hypertension (72 vs. 55%) compared to women with lower parity.
  • Women with grand multiparity had higher visceral adipose tissue (74.9 vs. 58.4 cm^3) and lower adiponectin concentration (5.79 vs. 7.61 microg/ml) compared to women with lower parity.

Sources:

  • Araneta, M. R., et al. (2010). Grand multiparity is associated with type 2 diabetes in Filipino American women, independent of visceral fat and adiponectin. Diabetes Care, 33(2), 385-389.
  • Type 2 Diabetes Epidemiology.

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