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Vaccines

Hepatitis B Virus Research Highlights Efficacy of Vaccines in Preventing Cancer

Strategic Insights

— 2 min read

Research out of the Department of Pathology has provided new insights into the efficacy of vaccines in preventing cancer caused by oncogenic viruses, including the hepatitis B virus. According to a study published in the journal Vaccines, prophylactic vaccines against HPV and HBV have been highly effective in preventing and reducing the incidence of uterine cervical and hepatocellular carcinomas. The study also noted that many endeavors for the development of vaccines against other oncogenic viruses have been met with limited success, apart from the very effective anti-HPV and anti-HBV vaccines in universal vaccination programs.

Key Takeaways:

  • The study highlights the effectiveness of prophylactic vaccines against HPV and HBV in preventing and reducing the incidence of uterine cervical and hepatocellular carcinomas.
  • The development of new vaccine technologies is hoped to lead to the creation of effective vaccines against other oncogenic viruses in the future.
  • The study noted that therapeutic vaccines are still mostly under evaluation and development, with limited success in experimental animals.
  • Identification of oncogenic viruses has made anti-viral vaccines a crucial tool for preventing and treating cancers caused by these viruses.
  • The study emphasized the importance of continued research and development in creating effective vaccines against oncogenic viruses.
  • The Department of Pathology researcher, Chi Sing Ng, noted that the development of new vaccine technologies holds promise for the creation of effective vaccines against oncogenic viruses in the future.
  • The study concluded that the efficacy of vaccines in preventing cancer caused by oncogenic viruses highlights the importance of vaccination programs in cancer prevention.

Statistics:

  • 30 years of literature research employing Scopus and Google Scholar using the keywords "oncogenic viruses, HPV, EBV, KSHHV, HHV8, Polyoma virus, HTLV-1, COVID-19, carcinoma, sarcoma, lymphoma, leukemia, anti-virus vaccines" was conducted as part of the study.
  • The study noted that prophylactic vaccines against HPV and HBV have been highly effective in preventing and reducing the incidence of uterine cervical and hepatocellular carcinomas.
  • According to the study, many endeavors for the development of vaccines against other oncogenic viruses have been met with limited success, apart from the very effective anti-HPV and anti-HBV vaccines in universal vaccination programs.
  • The study concluded that the development of effective vaccines against other oncogenic viruses in the future is hoped to be achieved with the development of new vaccine technologies.

Sources:

  • Immunotherapy of Oncovirus-Induced Cancers: A Review on the Development and Efficacy of Targeted Vaccines. Vaccines, 2025,13(9):911. (Vaccines - http://www.mdpi.com/journal/vaccines).
  • The publisher for Vaccines is MDPI AG.
  • A free version of this journal article is available at https://doi-org.sdpl.idm.oclc.org/10.3390/vaccines13090911.

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