Malnutrition in Pediatric Orthopaedic Surgery: High Complication Rates and Inconsistent Assessments

Pediatric orthopaedic surgeries for complex hip and spine conditions, particularly in children with cerebral palsy, are associated with high complication rates. Malnutrition, common in this population, contributes to poor wound healing, infections, and prolonged recovery. A new systematic review aims to evaluate the existing literature on perioperative nutritional assessment and optimization of pediatric patients undergoing complex hip and spine surgery.

Key Takeaways:

  • The study found that pediatric orthopaedic surgeries for complex hip and spine conditions have high complication rates, with posterior spinal fusion and hip reconstruction carrying complication rates over 50%.
  • Malnutrition is a significant contributor to poor wound healing, infections, and prolonged recovery in this population.
  • The study showed that isolated laboratory values are inconsistent predictors of malnutrition, but underweight status and weight loss are more reliable indicators of risk.
  • Enhanced recovery after surgery (ERAS) protocols incorporating nutritional strategies may improve outcomes, although more pediatric-focused data are needed.
  • The lack of standardized malnutrition definitions across studies limits comparability and hinders the development of evidence-based care pathways.
  • The study concluded that structured perioperative nutrition should be integrated into care pathways for pediatric orthopaedic patients.

Participants and Statistics:

  • The study included 371 studies, of which 23 met the inclusion criteria.
  • 18 studies were retrospective cohorts, 1 was a prospective cohort, 2 were cross-sectional, and 2 were case-control studies.
  • 15 studies were high quality (NOS 7).
  • 13 studies (57%) examined laboratory-based markers, while 10 (43%) assessed nutritional interventions or classifications.
  • Common outcomes included wound complications (48%), respiratory complications (26%), LOS/readmissions (26%), and patient-reported outcomes (17%).
  • Laboratory findings were inconsistent, but transferrin was associated with 10% weight loss.

Sources:

  • NewsRx, "New Malnutrition Study Findings Recently Were Reported by Researchers at University of California San Francisco (UCSF) (Perioperative Nutritional Optimization in Complex Pediatric Hip and Spine Surgery: A Systematic Review)." Pediatrics Week, November 1, 2025, p 71.
  • Perioperative Nutritional Optimization in Complex Pediatric Hip and Spine Surgery: A Systematic Review. Journal of Pediatric Orthopaedics, 2025.