New Insights into Non-Suicidal Self-Injury Behavior in Adolescents with Depressive Disorders

Investigators at Zhejiang Chinese Medical University have conducted a scoping review to examine the scope of non-suicidal self-injury (NSSI) behavior in adolescents with depressive disorders. The study aimed to systematically identify the factors affecting NSSI behavior and provide a reference for the construction of a risk-grading-based preventive intervention framework. The researchers analyzed 15 papers, including 1 guideline, 3 systematic evaluations, 1 literature review, and 10 cross-sectional studies, focusing on four categories: individual characteristics and psychological factors, illness and treatment factors, behaviors and lifestyles, and family and social environment.

Key Takeaways:

• Non-suicidal self-injury (NSSI) behavior is a major cause of death and disability in adolescents with depressive disorders, affecting their physical and mental health and quality of life.
• The study identified 15 papers examining NSSI behavior in adolescents with depressive disorders, including 1 guideline, 3 systematic evaluations, 1 literature review, and 10 cross-sectional studies.
• Factors affecting NSSI behaviors in adolescent patients with depression include individual characteristics and psychological traits, illness and treatment factors, behaviors and lifestyles, and family and social environment.
• The study emphasized the need to integrate relevant risk factors to create personalized prevention plans for adolescents with depressive disorders.
• Future research can focus on verifying the role of these risk factors in the predictive model and the effectiveness of intervention measures.

Statistics:

• 15 papers were included in the scoping review, comprising 1 guideline, 3 systematic evaluations, 1 literature review, and 10 cross-sectional studies.
• The study focused on four categories: individual characteristics and psychological factors (e.g., gender, age, sexual orientation), illness and treatment factors (duration of illness, degree of depression), behaviors and lifestyles (Internet addiction, stressful events), and family and social environment (family functioning, social support).
• A total of 10 cross-sectional studies were included in the analysis, examining various factors affecting NSSI behavior in adolescents with depressive disorders.

Sources:

• A review of the scope of non-suicidal self-injury behavior in adolescents with depressive disorders: an analysis of related influencing factors. BMC Psychiatry, 2025;25(1):913.
• BMC Psychiatry can be contacted at: Bmc, Campus, 4 Crinan St, London N1 9XW, England. (BioMed Central - www.biomedcentral.com/; BMC Psychiatry - www.biomedcentral.com/bmcpsychiatry/)
• Zhejiang Chinese Medical University.

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