Sign in Subscribe
Biochemistry

New Study Reveals Promising Alternative Source of Medical Collagen from Aurelia Aurita Jellyfish

Strategic Insights

— 1 min read

Research published by University Malaysia Sabah has made a significant breakthrough in wound and burn healing by discovering that biomass from the Aurelia aurita jellyfish can be a viable source of medical collagen. The study, which focused on the extraction of marine collagen using acetic acid, found that the jellyfish collagen possessed regenerative properties, increasing wound healing rates by 24.5%. This innovation holds great promise for the development of new healing methods, particularly in the fields of cosmetology and regenerative medicine.

Key Takeaways:

  • The study utilized biomass from the Aurelia aurita jellyfish as a source of medical collagen, demonstrating its potential as an alternative to traditional collagen sources.
  • Acetic acid was used as a means of marine collagen extraction from A. aurita biomass, yielding optimal conditions for maximal collagen yield at 0.5 M acetic acid and 48 h extraction time.
  • The collagen yield was found to be low at 0.0185%, but the high water holding capacity of the acid-soluble collagen sample showed good prospects for its use as a hemostatic sponge.
  • The molecular weight of the jellyfish collagen was determined to be within the range of 100-115 kDa, classifying it as type I collagen.
  • A. aurita jellyfish collagen revealed no cytotoxic properties, had no effect on adhesion, migration, and proliferation of keratinocytes, and did not affect the expression of cell differentiation markers.
  • The wound healing model demonstrated that the marine collagen increased wound healing rate by 24.5%, showcasing its regenerative properties.

Statistics:

  • 0.5 M acetic acid and 48 h extraction time yielded optimal conditions for maximal collagen yield.
  • 0.0185% was the reported collagen yield from A. aurita biomass.
  • 100-115 kDa was the molecular weight range of the A. aurita jellyfish collagen.
  • 24.5% was the increase in wound healing rate demonstrated by the marine collagen.

Sources:

  • Aurelia aurita jellyfish collagen: Recovery properties. Foods and Raw Materials, 2024,13(2):296-305. (Foods and Raw Materials - http://jfrm.ru)
  • Data on Extracellular Matrix Proteins Published by Researchers at University Malaysia Sabah (Aurelia aurita jellyfish collagen: Recovery properties). Life Science Weekly. October 21, 2025; p 480.

Read more