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Cancer

Perioperative Enteral Nutrition Reduces Muscle Wasting in Gastric Cancer Patients

Strategic Insights

— 2 min read

Patients who underwent gastric cancer surgery at a top-tier hospital in Nanjing, People's Republic of China, participated in a study on the impact of perioperative enteral nutrition on postoperative acute muscle wasting. The research, conducted at the Affiliated Jiangning Hospital of Nanjing Medical University, aimed to assess the effect of perioperative enteral nutrition on skeletal muscle mass, grip strength, and body weight in patients with gastric cancer. The study involved comparing the outcomes of two groups: one that received routine perioperative nutritional management and another that followed a preoperative combined with early postoperative enteral nutrition program. The results showed that the intervention significantly reduced the loss of skeletal muscle mass, grip strength, and body weight in the experimental group compared to the control group.

Key Takeaways:

  • The study was conducted on patients who underwent gastric cancer surgery at the Department of Gastrointestinal Oncology Surgery in a top-tier hospital in Nanjing, People's Republic of China.
  • The research aimed to assess the impact of perioperative enteral nutrition on postoperative acute muscle wasting in gastric cancer patients.
  • The study involved two groups: a control group that received routine perioperative nutritional management and an experimental group that followed a preoperative combined with early postoperative enteral nutrition program.
  • The results showed that the intervention significantly reduced the loss of skeletal muscle mass, grip strength, and body weight from baseline.
  • The study concluded that perioperative enteral nutrition provides a reference for clinical perioperative EN management in GC patients.
  • The study's findings may have implications for the management of gastric cancer patients undergoing surgery.

Statistics:

  • The study involved patients treated between January and June 2023 (control group) and July and December 2023 (experimental group).
  • The experimental group followed a preoperative combined with early postoperative enteral nutrition program compared to the control group, which received routine perioperative nutritional management.
  • The intervention significantly reduced the loss of skeletal muscle mass, grip strength, and body weight from baseline by [insert specific percentage or amount].
  • The study's findings may have implications for the management of gastric cancer patients undergoing surgery.

Sources:

  • Impact of perioperative enteral nutrition on postoperative acute muscle wasting in gastric cancer: a prospective exploratory study with a historical control group. Frontiers in Oncology, 2025;15:1607756.
  • NewsRx LLC. Findings from Affiliated Jiangning Hospital of Nanjing Medical University in the Area of Gastric Cancer Described (Impact of perioperative enteral nutrition on postoperative acute muscle wasting in gastric cancer: a prospective exploratory ...). Cancer Weekly. August 12, 2025; p 373.

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