Portable Smartphone-Assisted Detection Platform for Fluoroquinolone Residues

Researchers at the Henan University of Animal Husbandry and Economy have developed a portable smartphone-assisted detection platform for fluoroquinolone residues, which pose a significant risk to human health. The platform utilizes Terbium-Europium-Metal Organic Framework (Tb/Eu-MOF) nanomaterials to detect enrofloxacin, a representative sample of fluoroquinolones. This innovative approach offers a low-cost and portable method for detecting fluoroquinolone residues in food.

Key Takeaways:

  • The researchers synthesized five Tb/Eu-MOFs with different bimetallic proportions, with Tb/Eu-MOF (3:1) serving as the optimal sensing element.
  • The Tb/Eu-MOF nanomaterial suspension demonstrated a color change from orange-red to pale yellow as a result of fluorescence resonance energy transfer with ENR, achieving a limit of detection (LOD) of 0.004 mM and a broad linear range of 0.005-25 mM.
  • The researchers incorporated the Tb/Eu-MOF into an agar slice and coupled it with a smartphone for detection, improving portability and developing a smartphone-based agar slice platform.
  • This detection platform offers an innovative, low-cost, and portable approach for fluoroquinolone detection.
  • The researchers concluded that this method can be used for the detection of fluoroquinolone residues in food.
  • The study was conducted by a team of researchers led by Yiqian Zhang from the Henan University of Animal Husbandry and Economy.

Statistics:

  • LOD of 0.004 mM for the Tb/Eu-MOF nanomaterial suspension
  • Broad linear range of 0.005-25 mM for the Tb/Eu-MOF nanomaterial suspension
  • LOD of 4.7 mM for the smartphone-based agar slice platform
  • 5-150 mM linear range for the smartphone-based agar slice platform

Sources:

  • A portable smartphone-assisted Tb/Eu-MOF agar slice probes for the visual detection of fluoroquinolones. Food Chemistry, 2025;493:145733.
  • Research conducted by Yiqian Zhang, Dept. of Food and Bioengineering, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, People's Republic of China.
  • Article title: Study Results from Henan University of Animal Husbandry and Economy Provide New Insights into Nanomaterials (A portable smartphone-assisted Tb/Eu-MOF agar slice probes for the visual detection of fluoroquinolones). Nanotechnology Weekly. August 18, 2025; p 1633.