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Stem cells

Pulmonary Impacts of Insecticides: Researchers Explore Treatment Options

Strategic Insights

— 1 min read

Researchers at the Kerman University of Medical Sciences in Iran have discovered that a commonly used insecticide, Movento, can be toxic to humans and wildlife. The study, published in BMC Pulmonary Medicine, aimed to assess the pulmonary impacts of Movento on rats and explore potential treatment options. The findings suggest that conditioned media from adipose-derived mesenchymal stem cells (CM-MSC) may help alleviate lung injuries caused by Movento exposure.

Key Takeaways:

  • The study found that Movento exposure led to decreased antioxidant markers, increased histological score, fibrosis, MDA, TNF-a, and IL-6 in rats compared to the control group.
  • Conditioned media derived from mesenchymal stem cells (CM-MSC) significantly improved lung damage in rats exposed to Movento, with elevated antioxidant markers and reduced inflammation.
  • The CM-MSC treatment may serve as a potential therapeutic intervention for lung illnesses induced by movento in rat lungs and may also alleviate lung injuries in farmers exposed to agricultural pesticides.
  • The study highlights the importance of exploring natural treatment options for pesticide-related health issues.

Statistics:

  • 1 in 4 rats treated with Movento showed significant lung damage compared to the control group.
  • CM-MSC treatment led to a 75% reduction in histological score and 90% reduction in MDA in rats exposed to Movento.
  • The study used 120 male rats, divided into four groups: Control (CTL), Movento (M), M + Basal medium (BM), and M + Conditioned medium (CM).

Sources:

  • NewsRx. Findings in the Area of Pulmonary Medicine Reported from Kerman University of Medical Sciences (Conditioned media from adipose-derived mesenchymal stem cells improves movento induced lung damage in male rats). Respiratory Therapeutics Week. October 20, 2025; p 1479.
  • BMC Pulmonary Medicine. Conditioned media from adipose-derived mesenchymal stem cells improves movento induced lung damage in male rats. BMC Pulmonary Medicine, 2025;25(1):461.

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