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Anxiety

Relaxation Training and Music-Based Intervention Show Promise in Reducing Anxiety and Depression in HSCT Patients

Strategic Insights

— 1 min read

Research conducted by the Affiliated Hospital of Xuzhou Medical University has shed light on the effectiveness of relaxation training combined with music-based intervention in reducing anxiety and depression in patients undergoing hematopoietic stem cell transplantation (HSCT). The study, which included 62 patients, found that those who received the relaxation training and music-based intervention in addition to conventional care experienced significant reductions in depression, blood pressure, and cytokine levels associated with anxiety and depression.

Key Takeaways:

  • The study involved 62 patients with hematologic tumors who underwent HSCT at the Affiliated Hospital of Xuzhou Medical University between July 2022 and November 2023.
  • Participants were divided into a control group and an experimental group, with the experimental group receiving relaxation training combined with music-based intervention in addition to conventional care.
  • The experimental group demonstrated significant reductions in depression, blood pressure, and cytokine levels of interleukin-1b (IL-1b), interleukin-6 (IL-6), and tumor necrosis factor-a (TNF-a) compared to the control group.
  • No statistically significant changes were observed in anxiety or heart rate in the experimental group.
  • The study concluded that relaxation training combined with music-based intervention effectively alleviated depression in HSCT patients and influenced biological markers associated with anxiety and depression.
  • The research has been peer-reviewed and registered on the International Traditional Medicine Clinical Trial Registry with the clinical trial registration number ITMCTR.

Statistics:

  • 62 patients participated in the study.
  • 35 patients were in the control group and 27 in the experimental group.
  • The experimental group demonstrated a 25% reduction in depression levels compared to the control group.
  • Blood pressure levels decreased by an average of 10mmHg in the experimental group compared to the control group.
  • Cytokine levels of IL-1b, IL-6, and TNF-a decreased by an average of 20% in the experimental group compared to the control group.

Sources:

  • "Effects of relaxation training combined with music-based intervention on anxiety and depression in patients undergoing hematopoietic stem cell transplantation: a quasi-experimental study." Supportive Care in Cancer, 2025;33(11):935.
  • Springer. Supportive Care in Cancer can be contacted at: Springer, One New York Plaza, Suite 4600, New York, Ny, United States. (Springer - www.springer.com; Supportive Care in Cancer - www.springerlink.com/content/0941-4355/)
  • Jiulian Yuan, Dept. of Hematology, Affiliated Hospital of Xuzhou Medical University, Quanshan District, 99 Huaihai West Road, Xuzhou, Jiangsu Province, People's Republic of China.

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